Acute disseminated encephalomyelitis epidemiology and demographics: Difference between revisions
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===[[Epidemiology]]=== | ===[[Epidemiology]]=== | ||
*Average annual [[incidence]] is between 0.07 and 0.6 per 1,00,000 individuals per year<ref name="pmid24495742">{{cite journal| author=Xiong CH, Yan Y, Liao Z, Peng SH, Wen HR, Zhang YX | display-authors=etal| title=Epidemiological characteristics of acute disseminated encephalomyelitis in Nanchang, China: a retrospective study. | journal=BMC Public Health | year= 2014 | volume= 14 | issue= | pages= 111 | pmid=24495742 | doi=10.1186/1471-2458-14-111 | pmc=3922734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24495742 }} </ref> | *Average annual [[incidence]] is between 0.07 and 0.6 per 1,00,000 individuals per year<ref name="pmid24495742">{{cite journal| author=Xiong CH, Yan Y, Liao Z, Peng SH, Wen HR, Zhang YX | display-authors=etal| title=Epidemiological characteristics of acute disseminated encephalomyelitis in Nanchang, China: a retrospective study. | journal=BMC Public Health | year= 2014 | volume= 14 | issue= | pages= 111 | pmid=24495742 | doi=10.1186/1471-2458-14-111 | pmc=3922734 | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=24495742 }} </ref> <ref name="pmid19942388">{{cite journal| author=Torisu H, Kira R, Ishizaki Y, Sanefuji M, Yamaguchi Y, Yasumoto S | display-authors=etal| title=Clinical study of childhood acute disseminated encephalomyelitis, multiple sclerosis, and acute transverse myelitis in Fukuoka Prefecture, Japan. | journal=Brain Dev | year= 2010 | volume= 32 | issue= 6 | pages= 454-62 | pmid=19942388 | doi=10.1016/j.braindev.2009.10.006 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=19942388 }} </ref><ref name="pmid17219129">{{cite journal| author=Pohl D, Hennemuth I, von Kries R, Hanefeld F| title=Paediatric multiple sclerosis and acute disseminated encephalomyelitis in Germany: results of a nationwide survey. | journal=Eur J Pediatr | year= 2007 | volume= 166 | issue= 5 | pages= 405-12 | pmid=17219129 | doi=10.1007/s00431-006-0249-2 | pmc= | url=https://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17219129 }} </ref>. | ||
*Population based studies revealed a slightly lower [[incidence]] in the US and UK compared to Asian countries. The [[incidence]] of [[pediatric]] [[ADEM]] varies between 0.47/100000 and 0.64/100000 in the Asian countries compared to 0.07/100000 and 0.30/100000 in Europe and San Diego. | *Population based studies revealed a slightly lower [[incidence]] in the US and UK compared to Asian countries. The [[incidence]] of [[pediatric]] [[ADEM]] varies between 0.47/100000 and 0.64/100000 in the Asian countries compared to 0.07/100000 and 0.30/100000 in Europe and San Diego. | ||
* The [[incidence]] seems to be increasing with the distance from the Equator. | * The [[incidence]] seems to be increasing with the distance from the Equator. | ||
Revision as of 18:06, 13 November 2022
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Shameera Shaik Masthan MBBS, DLO, DNB[2]
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Overview
The incidence of acute disseminated encephalomyelitis reported to be 1 in 125,000-250,000 children aged 10 years or younger. The median age at onset is 3 to 7 yrs. It affects males and females in the ratio of 1.3 to 1. There is no racial predilection to the development of acute disseminated encephalomyelitis.
Epidemiology and Demographics
Epidemiology
- Average annual incidence is between 0.07 and 0.6 per 1,00,000 individuals per year[1] [2][3].
- Population based studies revealed a slightly lower incidence in the US and UK compared to Asian countries. The incidence of pediatric ADEM varies between 0.47/100000 and 0.64/100000 in the Asian countries compared to 0.07/100000 and 0.30/100000 in Europe and San Diego.
- The incidence seems to be increasing with the distance from the Equator.
Demographics
- ADEM is more common during childhood with a median age on onset between 5-8 years with a male predominance (1.8:1)
- The adult age of presentation ranges from 33 to 41 years without any gender predilection.
- No specific ethnic distribution has been described.
References
- ↑ Xiong CH, Yan Y, Liao Z, Peng SH, Wen HR, Zhang YX; et al. (2014). "Epidemiological characteristics of acute disseminated encephalomyelitis in Nanchang, China: a retrospective study". BMC Public Health. 14: 111. doi:10.1186/1471-2458-14-111. PMC 3922734. PMID 24495742.
- ↑ Torisu H, Kira R, Ishizaki Y, Sanefuji M, Yamaguchi Y, Yasumoto S; et al. (2010). "Clinical study of childhood acute disseminated encephalomyelitis, multiple sclerosis, and acute transverse myelitis in Fukuoka Prefecture, Japan". Brain Dev. 32 (6): 454–62. doi:10.1016/j.braindev.2009.10.006. PMID 19942388.
- ↑ Pohl D, Hennemuth I, von Kries R, Hanefeld F (2007). "Paediatric multiple sclerosis and acute disseminated encephalomyelitis in Germany: results of a nationwide survey". Eur J Pediatr. 166 (5): 405–12. doi:10.1007/s00431-006-0249-2. PMID 17219129.