Macroamylasemia: Difference between revisions
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'''Macroamylasemia''' is a benign acquired condition, characterized by a serum amylase unusually large in molecular size that has been found to occur in apparently healthy humans as well as in a variety of diseases including [[liver disease]], [[diabetes]], [[cancer]], [[malabsorption]] and [[autoimmune disorders]]. Most commonly macroamylasemia results from the formation of immune complexes between [[amylase]] and [[immunoglobulin]]s. | ==Overview== | ||
'''Macroamylasemia''' is a benign acquired condition, characterized by a serum [[amylase]] unusually large in molecular size that has been found to occur in apparently healthy humans as well as in a variety of diseases including [[liver disease]], [[diabetes]], [[cancer]], [[malabsorption]] and [[autoimmune disorders]]. Most commonly macroamylasemia results from the formation of immune complexes between [[amylase]] and [[immunoglobulin]]s. | |||
==Differential diagnosis of causes of macroamylasemia== | |||
Macroamylasemia has been associated with: | Macroamylasemia has been associated with: | ||
* [[Autoimmune disorders]] | |||
* [[Cancer]] | |||
* [[Celiac disease]] | * [[Celiac disease]] | ||
* [[Diabetes]] | |||
* [[HIV infection]] | * [[HIV infection]] | ||
* [[Liver disease]] | |||
* [[Lymphoma]] | * [[Lymphoma]] | ||
* [[Malabsorption]] | |||
* [[Monoclonal gammopathy]] | * [[Monoclonal gammopathy]] | ||
* [[Rheumatoid arthritis]] | * [[Rheumatoid arthritis]] |
Revision as of 16:46, 19 January 2009
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Overview
Macroamylasemia is a benign acquired condition, characterized by a serum amylase unusually large in molecular size that has been found to occur in apparently healthy humans as well as in a variety of diseases including liver disease, diabetes, cancer, malabsorption and autoimmune disorders. Most commonly macroamylasemia results from the formation of immune complexes between amylase and immunoglobulins.
Differential diagnosis of causes of macroamylasemia
Macroamylasemia has been associated with:
- Autoimmune disorders
- Cancer
- Celiac disease
- Diabetes
- HIV infection
- Liver disease
- Lymphoma
- Malabsorption
- Monoclonal gammopathy
- Rheumatoid arthritis
- Ulcerative colitis
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