Patent ductus arteriosus epidemiology and demographics: Difference between revisions
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==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
*The PDA is commonly found in infants and constitutes only 2% of all congenital defects found in adults. | *The PDA is commonly found in infants and constitutes only 2% of all congenital defects found in adults. | ||
*It is an isolated defect in 75% of cases, and is isolated in almost all adult cases. | *It is an isolated defect in 75% of cases, and is isolated in almost all adult cases. | ||
*In the United States, the estimated incidence in children born at term is between 0.02% and 0.06% of live births. | *In the United States, the estimated incidence in children born at term is between 0.02% and 0.06% of live births. | ||
*The incidence of patent ductus arteriosus has increased over the past few decades. This is in part due to increased survival in the premature infants. | |||
*The incidence is greater in children who are born- | *The incidence is greater in children who are born- | ||
**Prematurely, with a history of perinatal asphyxia. Perinatal asphyxia | **Prematurely, with a history of perinatal asphyxia. Perinatal asphyxia delays the closure of the ductus. Approximately, 20% of neonates with respiratory distress syndrome have a patent ductus arteriosus. In babies who are less than 1500 g at birth, many studies show the incidence of a PDA to exceed 30%. The increased patency in these groups is thought to be due to both [[hypoxia]] in babies with respiratory distress and immature ductal closure mechanisms in premature babies. | ||
**Children born at high altitude. | **Increased incidences in infants with congenital rubella. | ||
**Children born at high altitude. | |||
**The female-to-male ratio is 2:1 | **The female-to-male ratio is 2:1 | ||
Revision as of 14:00, 19 July 2011
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Associate Editor-In-Chief:Cafer Zorkun, M.D., Ph.D. [2]; Keri Shafer, M.D. [3] Priyamvada Singh, MBBS [[4]]
Assistant Editor-In-Chief: Kristin Feeney, B.S. [[5]]
Epidemiology and Demographics
- The PDA is commonly found in infants and constitutes only 2% of all congenital defects found in adults.
- It is an isolated defect in 75% of cases, and is isolated in almost all adult cases.
- In the United States, the estimated incidence in children born at term is between 0.02% and 0.06% of live births.
- The incidence of patent ductus arteriosus has increased over the past few decades. This is in part due to increased survival in the premature infants.
- The incidence is greater in children who are born-
- Prematurely, with a history of perinatal asphyxia. Perinatal asphyxia delays the closure of the ductus. Approximately, 20% of neonates with respiratory distress syndrome have a patent ductus arteriosus. In babies who are less than 1500 g at birth, many studies show the incidence of a PDA to exceed 30%. The increased patency in these groups is thought to be due to both hypoxia in babies with respiratory distress and immature ductal closure mechanisms in premature babies.
- Increased incidences in infants with congenital rubella.
- Children born at high altitude.
- The female-to-male ratio is 2:1