Transposition of the great vessels historical perspective

Transposition of the great vessels Microchapters
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Dextro-transposition of the great arteries
L-transposition of the great arteries
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, M.B.B.S. [2]; Cafer Zorkun, M.D., Ph.D. [3]; Keri Shafer, M.D. [4]; Assistant Editor(s)-In-Chief: Kristin Feeney, B.S. [5]

Overview

Historical overview

• The TGA was first described in 1797 by Matthew Baillie as a "singular malformation"
• In 1814 Farre described it as "transposition".
• No treatment was available until the middle of the 20th century.
• In the 1950s, surgical atrial septectomy was developed followed by balloon atrial septostomy in the 1960s. These surgical therapies were not curative, but were palliative. They were later followed by physiological procedures.
• Today, the survival rate for infants with TGA is greater than 90%.