Thrombosis causes: Difference between revisions
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* by a blood state of hypercoagulability (caused for example, by genetic deficiencies or autoimmune disorders). | * by a blood state of hypercoagulability (caused for example, by genetic deficiencies or autoimmune disorders). | ||
High altitude has also been known to induce thrombosis | High altitude has also been known to induce thrombosis <ref name="pmid17896862">{{cite journal| author=Kuipers S, Cannegieter SC, Middeldorp S, Robyn L, Büller HR, Rosendaal FR| title=The absolute risk of venous thrombosis after air travel: a cohort study of 8,755 employees of international organisations. | journal=PLoS Med | year= 2007 | volume= 4 | issue= 9 | pages= e290 | pmid=17896862 | doi=10.1371/journal.pmed.0040290 | pmc=PMC1989755 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=17896862 }} </ref>. Occasionally, abnormalities in [[coagulation]] are to blame. | ||
Intravascular [[coagulation]] follows, forming a structureless mass of [[red blood cell]]s, [[leukocyte]]s, and [[fibrin]]. | Intravascular [[coagulation]] follows, forming a structureless mass of [[red blood cell]]s, [[leukocyte]]s, and [[fibrin]]. | ||
Revision as of 17:34, 30 August 2011
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Thrombosis Microchapters |
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Site of Thrombosis |
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Differentiating Thrombosis from other Diseases |
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Thrombosis causes On the Web |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Associate Editors-in-Chief: Ujjwal Rastogi, MBBS [2]
Etiology
Classically, thrombosis is caused by abnormalities in one or more of the following (Virchow's triad):
- The composition of the blood (hypercoagulability)
- Quality of the vessel wall (endothelial cell injury)
- Nature of the blood flow (hemostasis)
The formation of a thrombus is usually caused by the top three causes, known as Virchow's triad. To elaborate, the pathogenesis includes:
- an injury to the vessel's wall (such as by trauma, infection, or turbulent flow at bifurcations)
- by the slowing or stagnation of blood flow past the point of injury (which may occur after long periods of sendentary behavior - for example, sitting on a long airplane flight
- by a blood state of hypercoagulability (caused for example, by genetic deficiencies or autoimmune disorders).
High altitude has also been known to induce thrombosis [1]. Occasionally, abnormalities in coagulation are to blame.
Intravascular coagulation follows, forming a structureless mass of red blood cells, leukocytes, and fibrin.
<youtube v=AiC1V5zAba4/>
References
- ↑ Kuipers S, Cannegieter SC, Middeldorp S, Robyn L, Büller HR, Rosendaal FR (2007). "The absolute risk of venous thrombosis after air travel: a cohort study of 8,755 employees of international organisations". PLoS Med. 4 (9): e290. doi:10.1371/journal.pmed.0040290. PMC 1989755. PMID 17896862.
cs:Trombóza de:Thrombose eo:Trombozo it:Trombosi he:תרומבוס ms:Trombotik nl:Trombose fi:Verihiutale