Thrombosis causes: Difference between revisions
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These three conditions are collectively known as [[Virchow's triad]] and lead to intravascular [[coagulation]], forming a mass of [[red blood cell]]s, [[leukocyte]]s, and [[fibrin]]. | These three conditions are collectively known as [[Virchow's triad]] and lead to intravascular [[coagulation]], forming a mass of [[red blood cell]]s, [[leukocyte]]s, and [[fibrin]]. | ||
<youtube v=X_POCRsy7i4/> | <youtube v=X_POCRsy7i4/> This video explains the process of thrombosis | ||
===Other Less Known Causes=== | ===Other Less Known Causes=== | ||
Revision as of 21:22, 3 September 2011
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Thrombosis Microchapters |
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Site of Thrombosis |
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Differentiating Thrombosis from other Diseases |
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Diagnosis |
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Treatment |
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Thrombosis causes On the Web |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editors-in-Chief: Ujjwal Rastogi, MBBS [2]
Overview
Rudolf Virchow noted several factors affecting the clot formation, which are:
1).Alterations in blood flow (stasis) : Blood flows throughout the circulatory system, without significantly stopping or slowing any where. In certain pathological conditions where the blood flow slows down or stops, it causes
- a) Increase in platelet to endothelium contact
- b) Decrease the dilution of clotting factors
This increases the risk of clot formation and form microthrombi, which further grow and propagate.
2).Injury to the vascular endothelium : Intrinsic or secondary to external trauma (Eg. catheterization) can cause intimal damage and stimulates clot formation. See Coagulation
3).Alterations in the constitution of blood (hypercoagulability) :It is the propensity to develop thrombosis due to an abnormality in the system of coagulation.
These three conditions are collectively known as Virchow's triad and lead to intravascular coagulation, forming a mass of red blood cells, leukocytes, and fibrin.
<youtube v=X_POCRsy7i4/> This video explains the process of thrombosis
Other Less Known Causes
High altitude has also been known to induce thrombosis [1]. Occasionally, abnormalities in coagulation are to blame.
References
- ↑ Kuipers S, Cannegieter SC, Middeldorp S, Robyn L, Büller HR, Rosendaal FR (2007). "The absolute risk of venous thrombosis after air travel: a cohort study of 8,755 employees of international organisations". PLoS Med. 4 (9): e290. doi:10.1371/journal.pmed.0040290. PMC 1989755. PMID 17896862.
cs:Trombóza de:Thrombose eo:Trombozo it:Trombosi he:תרומבוס ms:Trombotik nl:Trombose fi:Verihiutale