Aspergillosis: Difference between revisions
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==Overview== | ==Overview== | ||
'''''Aspergillosis''''' is the name given to a wide variety of diseases caused by the [[genus]] of [[fungi]] ''[[Aspergillus]]''. The most common forms are [[allergic bronchopulmonary aspergillosis]], pulmonary [[aspergilloma]] and invasive aspergillosis. Compromised [[immune system]]s often allow ''Aspergillus'' to colonize. | '''''Aspergillosis''''' is the name given to a wide variety of diseases caused by the [[genus]] of [[fungi]] ''[[Aspergillus]]''. The most common forms are [[allergic bronchopulmonary aspergillosis]], pulmonary [[aspergilloma]] and invasive aspergillosis. Compromised [[immune system]]s often allow ''Aspergillus'' to colonize. | ||
==Diagnosis== | ==Diagnosis== | ||
Revision as of 15:52, 26 January 2012
| Aspergillosis | |
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| Histopathologic image of pulmonary invasive aspergillosis in a patient with interstitial pneumonia. Autopsy material. Grocott's methenamine silver stain. | |
| ICD-10 | B44 |
| ICD-9 | 117.3 |
| MedlinePlus | 001326 |
| MeSH | D001228 |
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Aspergillosis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Aspergillosis On the Web |
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American Roentgen Ray Society Images of Aspergillosis |
For patient information click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Aspergillosis is the name given to a wide variety of diseases caused by the genus of fungi Aspergillus. The most common forms are allergic bronchopulmonary aspergillosis, pulmonary aspergilloma and invasive aspergillosis. Compromised immune systems often allow Aspergillus to colonize.
Diagnosis
On chest X-ray and computed tomography pulmonary aspergillosis classically manifests as an air crescent sign.[1]
Treatment
The drugs amphotericin B, caspofungin, flucytosine, itraconazole, voriconazole [2] are used to treat this fungal infection.
Notable Outbreaks
Aspergillosis has been the culprit in several recent rapid die-offs among waterfowl. From December 8-14, 2006 over 2,000 Mallards died in the Burley, Idaho area, an agricultural community approximately 150 miles southeast of Boise. Moldy waste grain from the farmland and feedlots in the area is the suspected source. A similar aspergillosis outbreak killed 500 mallards in Iowa in 2005. Moldy grain was the cause in that case.
Mallards and other ducks are particularly susceptible to Aspergillosis as they will often resort to poor food sources during bad weather.
Albeit relatively rare in humans, aspergillosis is a common and dangerous infection in birds, particularly in pet parrots and parakeets.
While there is no connection between Aspergillosis and the H5N1 strain of Avian Influenza (commonly called "bird flu"), the rapid die-offs it causes can spark fears of a bird-flu outbreak in the communities where the die-offs occur. There is no outwardly visible sign off the fungal infection as the cause; laboratory analysis is the only way to prove or disprove bird-flu or Aspergillosis.
References
- ↑ Curtis A, Smith G, Ravin C (1979). "Air crescent sign of invasive aspergillosis". Radiology. 133 (1): 17–21. PMID 472287. Unknown parameter
|month=ignored (help) - ↑ Herbrecht R, Denning D, Patterson T, Bennett J, Greene R, Oestmann J, Kern W, Marr K, Ribaud P, Lortholary O, Sylvester R, Rubin R, Wingard J, Stark P, Durand C, Caillot D, Thiel E, Chandrasekar P, Hodges M, Schlamm H, Troke P, de Pauw B; Invasive Fungal Infections Group of the European Organisation for Research and Treatment of Cancer and the Global Aspergillus Study Group. (2002). "Voriconazole versus amphotericin B for primary therapy of invasive aspergillosis". N Engl J Med. 347 (6): 408–15. PMID 12167683. Unknown parameter
|month=ignored (help)
External links
- Aspergillus - aspergillus.org.uk
- Aspergillosis -doctorfungus.org
- USGS National Wildlife Health Center - www.nwhc.usgs.gov
de:Aspergillose hr:Aspergiloza nl:Aspergillose uk:Аспергільоз }