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{{CMG}}; '''Associate Editors-In-Chief:''' [[User:Mohammed Sbeih|Mohammed A. Sbeih, M.D.]] [mailto:msbeih@perfuse.org]; '''Assistant Editor-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@perfuse.org]
{{CMG}}; '''Associate Editor(s)-In-Chief:''' [[User:Mohammed Sbeih|Mohammed A. Sbeih, M.D.]] [mailto:msbeih@perfuse.org]; {{LG}}; '''Assistant Editor-In-Chief:''' [[Kristin Feeney|Kristin Feeney, B.S.]] [mailto:kfeeney@perfuse.org]


==Overview==
==Overview==
Aortic stenosis is a major health problem primarily affecting older adults. As North American and European populations continue to live longer, aortic stenosis has major public health implications.  Abnormalities of aortic valve morphology and function represent the most common cardiac-valve lesion in the elderly. The etiology of aortic stenosis is degenerative-calcific in the majority of patients.
[[Aortic stenosis]] is a major health problem primarily affecting older adults and majority is due to [[calcific aortic valve disease|calcific]] [[degeneration]]. [[Aortic stenosis]] tends to affect approximately 2% of patients over the age of 65, 3% the age of 75, and 4% over the age 85.<ref name="pmid9060903">{{cite journal |author=Stewart BF, Siscovick D, Lind BK, Gardin JM, Gottdiener JS, Smith VE, Kitzman DW, Otto CM |title=Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study |journal=[[Journal of the American College of Cardiology]] |volume=29 |issue=3 |pages=630–4 |year=1997 |month=March |pmid=9060903 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0735109796005633 |accessdate=2012-04-11}}</ref>


==Prevalence==
==Demographics==
Aortic '''''stenosis''''' is a common problem found predominantly in middle age to older adults. Less than 1% of all live births exhibit symptoms of severe aortic stenosis. The prevalence of aortic stenosis increases with age. Approximately 2% of people over the age of 65, 3% of people over age 75, and 4% of people over age 85 have the disorder. In North America and Europe, a linear relationship exists between an aging population and an increase in aortic stenosis.
===Age===
The prevalence of [[aortic stenosis]] increases with age. Less than 1% of all live births exhibit symptoms of [[severe aortic stenosis]]. Approximately 2% of patients over the age of 65, 3% over the age of 75, and 4% over the age of 85 have [[aortic stenosis]].<ref name="pmid9060903">{{cite journal |author=Stewart BF, Siscovick D, Lind BK, Gardin JM, Gottdiener JS, Smith VE, Kitzman DW, Otto CM |title=Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study |journal=[[Journal of the American College of Cardiology]] |volume=29 |issue=3 |pages=630–4 |year=1997 |month=March |pmid=9060903 |doi= |url=http://linkinghub.elsevier.com/retrieve/pii/S0735109796005633 |accessdate=2012-04-11}}</ref>


Aortic valve '''''sclerosis''''' (aortic valve thickening and calcification without pressure gradient)  affects about one fourth of adults over 65 years of age. There is an increased prevalence of both stenosis and sclerosis with aging (4% and 48% respectively in those over 85 years).
===Developed Countries===
 
In North America and Europe, a linear relationship exists between an aging population and an increase in the incidence of [[aortic stenosis]].
In the Cardiovascular Health Study, the Doppler echocardiographic examination performed in 5,621 subjects older than 65 year without prevalent cardiovascular disease at entry identified an aortic ''sclerosis'' (valve thickening) in 29% of overall population and an aortic ''stenosis'' (valve abnormalities and instantaneous pressure gradient >25 mmHg) in 2% <ref name="pmid9060903">{{cite journal| author=Stewart BF, Siscovick D, Lind BK, Gardin JM, Gottdiener JS, Smith VE et al.| title=Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study. | journal=J Am Coll Cardiol | year= 1997 | volume= 29 | issue= 3 | pages= 630-4 | pmid=9060903 | doi= | pmc= | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=9060903  }} </ref>.
 
==Sources==
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC1550260/


==References==
==References==

Revision as of 18:43, 11 April 2012

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-In-Chief: Mohammed A. Sbeih, M.D. [2]; Lakshmi Gopalakrishnan, M.B.B.S. [3]; Assistant Editor-In-Chief: Kristin Feeney, B.S. [4]

Overview

Aortic stenosis is a major health problem primarily affecting older adults and majority is due to calcific degeneration. Aortic stenosis tends to affect approximately 2% of patients over the age of 65, 3% the age of 75, and 4% over the age 85.[1]

Demographics

Age

The prevalence of aortic stenosis increases with age. Less than 1% of all live births exhibit symptoms of severe aortic stenosis. Approximately 2% of patients over the age of 65, 3% over the age of 75, and 4% over the age of 85 have aortic stenosis.[1]

Developed Countries

In North America and Europe, a linear relationship exists between an aging population and an increase in the incidence of aortic stenosis.

References

  1. 1.0 1.1 Stewart BF, Siscovick D, Lind BK, Gardin JM, Gottdiener JS, Smith VE, Kitzman DW, Otto CM (1997). "Clinical factors associated with calcific aortic valve disease. Cardiovascular Health Study". Journal of the American College of Cardiology. 29 (3): 630–4. PMID 9060903. Retrieved 2012-04-11. Unknown parameter |month= ignored (help)


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