Papilledema pathophysiology: Difference between revisions
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* [[Optic nerve]] sheath is continuous with the [[subarachnoid space]] of the [[brain]] and is regarded as an extension of the [[central nervous system]]. | * [[Optic nerve]] sheath is continuous with the [[subarachnoid space]] of the [[brain]] and is regarded as an extension of the [[central nervous system]]. | ||
* The brain itself is relatively spared from pathological consequences of high pressure. | * The cranium and the [[vertebral body]], along with the relatively inelastic dura, form a rigid container, such that the increase in any of its contents—brain, blood and cerebrospinal fluid can cause [[increased intracranial pressure]]. | ||
* The brain itself is relatively spared from pathological consequences of high pressure. | |||
* [[Increased intracranial pressure]] is transmitted through to the optic nerve via this [[optic nerve]] sheath. | * [[Increased intracranial pressure]] is transmitted through to the optic nerve via this [[optic nerve]] sheath. |
Revision as of 18:33, 17 July 2012
Papilledema |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-In-Chief:Kalsang Dolma
Overview
Papilledema results due to transmission of increased intracranial pressure to the anterior end of optic nerve through optic nerve sheath.
Pathophysiology
- Optic nerve sheath is continuous with the subarachnoid space of the brain and is regarded as an extension of the central nervous system.
- The cranium and the vertebral body, along with the relatively inelastic dura, form a rigid container, such that the increase in any of its contents—brain, blood and cerebrospinal fluid can cause increased intracranial pressure.
- The brain itself is relatively spared from pathological consequences of high pressure.
- Increased intracranial pressure is transmitted through to the optic nerve via this optic nerve sheath.
- The anterior end of the optic nerve stops abruptly at the eye. Hence the pressure is asymmetrical and this causes a pinching and protrusion of the optic nerve at its head.
- The fibers of the retinal ganglion cells of the optic disc become engorged and bulge anteriorly.
- Persistent and extensive optic nerve head swelling, or optic disc edema, can lead to loss of these fibers and permanent visual impairment.