Danaparoid: Difference between revisions
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==Overview== | |||
'''Danaparoid sodium''' (Orgaran®) is an [[anticoagulant]] that works by inhibiting activated [[factor X]] (factor Xa). | '''Danaparoid sodium''' (Orgaran®) is an [[anticoagulant]] that works by inhibiting activated [[factor X]] (factor Xa). | ||
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==Administration== | ==Administration== | ||
[[Parenteral|IV]] | * [[Parenteral|IV]] | ||
* SC | |||
==Side | ==Side Effects== | ||
*Bleeding problems | *Bleeding problems | ||
*[[Thrombocytopenia|Low platelets]], due to a low level of structural similarity between danaparoid and [[heparin]] | *[[Thrombocytopenia|Low platelets]], due to a low level of structural similarity between danaparoid and [[heparin]] | ||
*[[Asthma]] exacerbations, due to allergies to [[sulphite]]s contained within the medicine | *[[Asthma]] exacerbations, due to allergies to [[sulphite]]s contained within the medicine | ||
==External Links== | |||
==External | |||
* {{MeshName|danaparoid}} | * {{MeshName|danaparoid}} | ||
{{Antithrombotics}} | {{Antithrombotics}} | ||
==References== | |||
{{reflist|2}} | |||
[[Category: | {{Antithrombotics}} | ||
[[Category:Drug]] | |||
[[Category:Cardiovascular Drugs]] | |||
[[Category:Anticoagulants]] | [[Category:Anticoagulants]] | ||
Revision as of 00:51, 26 July 2014
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E number | {{#property:P628}} |
ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
WikiDoc Resources for Danaparoid |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Danaparoid sodium (Orgaran®) is an anticoagulant that works by inhibiting activated factor X (factor Xa).
Danaparoid is considered a "low molecular weight heparin" by some sources, but is chemically distinct from heparin and thus has little cross-reactivity in heparin-intolerant patients.
Uses
It is used to prevent deep venous clots, particularly in situations with a high risk of clot formation, such as after hip surgery.
It is also used as a heparinoid substitute in heparin-induced thrombocytopenia which may otherwise cause paradoxical thrombosis.
Discontinuation
On August 14, 2002, this drug was withdrawn by Organon International.[1]
Administration
- IV
- SC
Side Effects
- Bleeding problems
- Low platelets, due to a low level of structural similarity between danaparoid and heparin
- Asthma exacerbations, due to allergies to sulphites contained within the medicine
External Links
- danaparoid at the US National Library of Medicine Medical Subject Headings (MeSH)
References
- Pages with script errors
- E number from Wikidata
- ECHA InfoCard ID from Wikidata
- Infobox drug articles without a structure image
- Chemical articles without CAS registry number
- Articles without EBI source
- Chemical pages without ChemSpiderID
- Chemical pages without DrugBank identifier
- Articles without KEGG source
- Articles without InChI source
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- Drugs with no legal status
- Articles containing unverified chemical infoboxes
- Drug
- Cardiovascular Drugs
- Anticoagulants