Rheumatoid arthritis causes: Difference between revisions
Jump to navigation
Jump to search
Created page with "{{Rheumatoid arthritis}} {{CMG}} {{AE}} {{AN}} ==Overview== ==Causes== The cause of RA is still unknown to this day. In considering possible causes, it is important to distin..." |
No edit summary |
||
| Line 4: | Line 4: | ||
==Overview== | ==Overview== | ||
==Causes== | ==Causes== | ||
The cause of RA is still unknown to this day. In considering possible causes, it is important to distinguish between the cause(s) that trigger the inflammatory process, and those that may permit it to persist and even progress from milder to more severe forms of inflammation. Thus, it has long been suspected that certain infections could be triggers for this disease. As in other autoimmune diseases, the "mistaken identity" theory suggests that an offending organism causes an immune response that leaves behind antibodies that are specific to that organism. The antibodies are not specific enough, though. They begin an immune attack against, in this case, the [[synovium]], because some molecule in the synovium "looks like" a molecule on the offending organism that created the initial immune reaction - this phenomenon is called [[molecular mimicry]]. | *The cause of RA is still unknown to this day. | ||
*In considering possible causes, it is important to distinguish between the cause(s) that trigger the inflammatory process, and those that may permit it to persist and even progress from milder to more severe forms of inflammation. | |||
*Thus, it has long been suspected that certain infections could be triggers for this disease. As in other autoimmune diseases, the "mistaken identity" theory suggests that an offending organism causes an immune response that leaves behind antibodies that are specific to that organism. | |||
*The antibodies are not specific enough, though. They begin an immune attack against, in this case, the [[synovium]], because some molecule in the synovium "looks like" a molecule on the offending organism that created the initial immune reaction - this phenomenon is called [[molecular mimicry]]. | |||
==References== | ==References== | ||
Revision as of 12:17, 22 August 2012
|
Rheumatoid arthritis Microchapters | |
|
Diagnosis | |
|---|---|
|
Treatment | |
|
Case Studies | |
|
Rheumatoid arthritis causes On the Web | |
|
American Roentgen Ray Society Images of Rheumatoid arthritis causes | |
|
Risk calculators and risk factors for Rheumatoid arthritis causes | |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]
Overview
Causes
- The cause of RA is still unknown to this day.
- In considering possible causes, it is important to distinguish between the cause(s) that trigger the inflammatory process, and those that may permit it to persist and even progress from milder to more severe forms of inflammation.
- Thus, it has long been suspected that certain infections could be triggers for this disease. As in other autoimmune diseases, the "mistaken identity" theory suggests that an offending organism causes an immune response that leaves behind antibodies that are specific to that organism.
- The antibodies are not specific enough, though. They begin an immune attack against, in this case, the synovium, because some molecule in the synovium "looks like" a molecule on the offending organism that created the initial immune reaction - this phenomenon is called molecular mimicry.