Acute liver failure surgery: Difference between revisions
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Created page with "__NOTOC__ {{Acute liver failure}} {{CMG}} ==Overview== ==Surgery== * Drainage of ascites * While many people who develop acute liver failure recover with supportive treatm..." |
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* "[[Liver dialysis]]" (various measures to replace normal liver function) is evolving as a treatment modality and is gradually being introduced in the care of patients with liver failure. | * "[[Liver dialysis]]" (various measures to replace normal liver function) is evolving as a treatment modality and is gradually being introduced in the care of patients with liver failure. | ||
===Liver Transplantation=== | ===Liver Transplantation=== | ||
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|-style="background-color:#FFE4E1; align:center; color:#8B4513; text-align: center" | |||
|'''King's College Hospital criteria''' <br /> | |||
'''for liver transplantation in acute liver failure<ref>{{cite journal |author=O'Grady JG, Alexander GJ, Hayllar KM, Williams R |title=Early indicators of prognosis in fulminant hepatic failure |journal=Gastroenterology |volume=97 |issue=2 |pages=439-45 |year=1989 |pmid=2490426 |doi=}}</ref>''' | |||
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|'''Patients with [[paracetamol]] toxicity'''<br /> | |||
pH <7.3 or<br /> | |||
[[Prothrombin time]] >100 seconds and<br /> [[serum creatinine]] level >3.4 mg/dL (>300 μmol/l)<br /> | |||
if in grade III or IV [[hepatic encephalopathy|encephalopathy]] | |||
|- | |||
|'''Other patients'''<br /> | |||
Prothrombin time >100 seconds or <br /> | |||
''Three of the following variables'':<br /> | |||
*Age <10 yr or >40 yr | |||
*Cause: | |||
** non-A, non-B hepatitis | |||
** [[halothane]] hepatitis | |||
** idiosyncratic drug reaction | |||
*Duration of jaundice before encephalopathy >7 days | |||
*prothrombin time >50 seconds | |||
*Serum [[bilirubin]] level >17.6 mg/dL (>300 μmol/l) | |||
|} | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} |
Revision as of 20:21, 28 August 2012
Acute liver failure Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Surgery
- Drainage of ascites
- While many people who develop acute liver failure recover with supportive treatment, liver transplantation is often required in people who continue to deteriorate or have adverse prognostic factors.
- "Liver dialysis" (various measures to replace normal liver function) is evolving as a treatment modality and is gradually being introduced in the care of patients with liver failure.
Liver Transplantation
King's College Hospital criteria for liver transplantation in acute liver failure[1] |
Patients with paracetamol toxicity pH <7.3 or |
Other patients Prothrombin time >100 seconds or |