Ankylosing spondylitis laboratory findings: Difference between revisions
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==Overview== | ==Overview== | ||
There is no direct test to diagnose AS. A clinical examination and [[X-ray]] studies of the spine, which show characteristic spinal changes and [[Sacroiliac joint|sacroiliitis]], are the major diagnostic tools. A drawback of X-ray diagnosis is that signs and symptoms of AS have usually been established as long as 8-10 years prior to X-ray evident changes occurring on a plain film X-ray, which means a delay of as long as 10 years before adequate therapies can be introduced. An option for more accurate (and much earlier) diagnosis are [[Computed tomography|tomography]] and [[magnetic resonance imaging]] of the sacroiliac joints. The [[Schober's test]] is a useful clinical measure of flexion of the lumbar spine performed during examination.<ref>{{cite journal | author = Thomas E, Silman AJ, Papageorgiou AC, Macfarlane GJ, Croft PR. | title = Association between measures of spinal mobility and low back pain. An analysis of new attenders in primary care. | journal = Spine | volume = 23 | issue = 2 | pages = 343-7 | year = 1998 | id = PMID 9507623}}</ref> | There is no direct test to diagnose AS. A clinical examination and [[X-ray]] studies of the spine, which show characteristic spinal changes and [[Sacroiliac joint|sacroiliitis]], are the major diagnostic tools. A drawback of X-ray diagnosis is that signs and symptoms of AS have usually been established as long as 8-10 years prior to X-ray evident changes occurring on a plain film X-ray, which means a delay of as long as 10 years before adequate therapies can be introduced. An option for more accurate (and much earlier) diagnosis are [[Computed tomography|tomography]] and [[magnetic resonance imaging]] of the sacroiliac joints. The [[Schober's test]] is a useful clinical measure of flexion of the lumbar spine performed during examination.<ref>{{cite journal | author = Thomas E, Silman AJ, Papageorgiou AC, Macfarlane GJ, Croft PR. | title = Association between measures of spinal mobility and low back pain. An analysis of new attenders in primary care. | journal = Spine | volume = 23 | issue = 2 | pages = 343-7 | year = 1998 | id = PMID 9507623}}</ref> | ||
==Laboratory Findings== | ==Laboratory Findings== | ||
[[Image:Ankylosing process.jpg|left|thumb|256px|The ankylosis process.]] | |||
Increase in | Increase in | ||
*[[C-Reactive protein|C-reactive protein]] (CRP) and | *[[C-Reactive protein|C-reactive protein]] (CRP) and | ||
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==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
[[Category:Arthritis]] | |||
[[Category:Autoimmune diseases]] | |||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
There is no direct test to diagnose AS. A clinical examination and X-ray studies of the spine, which show characteristic spinal changes and sacroiliitis, are the major diagnostic tools. A drawback of X-ray diagnosis is that signs and symptoms of AS have usually been established as long as 8-10 years prior to X-ray evident changes occurring on a plain film X-ray, which means a delay of as long as 10 years before adequate therapies can be introduced. An option for more accurate (and much earlier) diagnosis are tomography and magnetic resonance imaging of the sacroiliac joints. The Schober's test is a useful clinical measure of flexion of the lumbar spine performed during examination.[1]
Laboratory Findings
Increase in
- C-reactive protein (CRP) and
- Erythrocyte sedimentation rate (ESR).
References
- ↑ Thomas E, Silman AJ, Papageorgiou AC, Macfarlane GJ, Croft PR. (1998). "Association between measures of spinal mobility and low back pain. An analysis of new attenders in primary care". Spine. 23 (2): 343–7. PMID 9507623.