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| <!-- The PBB_Controls template provides controls for Protein Box Bot, please see Template:PBB_Controls for details. --> | | {{Infobox_gene}} |
| {{PBB_Controls | | '''Olfactory receptor 2L13''' is a [[protein]] that in humans is encoded by the ''OR2L13'' [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2L13 olfactory receptor, family 2, subfamily L, member 13| url = https://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=284521| accessdate = }}</ref> |
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| | update_protein_box = yes
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| | update_summary = yes
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| | update_citations = yes | |
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| <!-- The GNF_Protein_box is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
| | == Function == |
| {{GNF_Protein_box
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| | image =
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| | image_source =
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| | PDB =
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| | Name = Olfactory receptor, family 2, subfamily L, member 13
| |
| | HGNCid = 19578
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| | Symbol = OR2L13
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| | AltSymbols =; MGC40047; OR2L14
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| | OMIM =
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| | ECnumber =
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| | Homologene = 88350
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| | MGIid = 3030000
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| | Function = {{GNF_GO|id=GO:0004872 |text = receptor activity}} {{GNF_GO|id=GO:0004984 |text = olfactory receptor activity}}
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| | Component = {{GNF_GO|id=GO:0016020 |text = membrane}} {{GNF_GO|id=GO:0016021 |text = integral to membrane}}
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| | Process = {{GNF_GO|id=GO:0007165 |text = signal transduction}} {{GNF_GO|id=GO:0007186 |text = G-protein coupled receptor protein signaling pathway}} {{GNF_GO|id=GO:0007608 |text = sensory perception of smell}} {{GNF_GO|id=GO:0050896 |text = response to stimulus}}
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| | Orthologs = {{GNF_Ortholog_box
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| | Hs_EntrezGene = 284521
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| | Hs_Ensembl = ENSG00000196071
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| | Hs_RefseqProtein = NP_787107
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| | Hs_RefseqmRNA = NM_175911
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| | Hs_GenLoc_db =
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| | Hs_GenLoc_chr = 1
| |
| | Hs_GenLoc_start = 246328574
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| | Hs_GenLoc_end = 246330920
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| | Hs_Uniprot = Q8N349
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| | Mm_EntrezGene = 259071
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| | Mm_Ensembl = ENSMUSG00000056822
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| | Mm_RefseqmRNA = NM_147068
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| | Mm_RefseqProtein = NP_667279
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| | Mm_GenLoc_db =
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| | Mm_GenLoc_chr = 16
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| | Mm_GenLoc_start = 19400403
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| | Mm_GenLoc_end = 19401341
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| | Mm_Uniprot =
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| }}
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| }}
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| '''Olfactory receptor, family 2, subfamily L, member 13''', also known as '''OR2L13''', is a human [[gene]].<ref name="entrez">{{cite web | title = Entrez Gene: OR2L13 olfactory receptor, family 2, subfamily L, member 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=284521| accessdate = }}</ref>
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| <!-- The PBB_Summary template is automatically maintained by Protein Box Bot. See Template:PBB_Controls to Stop updates. -->
| | Olfactory receptors interact with odorant [[molecule]]s in the nose, to initiate a [[neuron]]al response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez" /> |
| {{PBB_Summary
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| | section_title =
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| | summary_text = Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.<ref name="entrez">{{cite web | title = Entrez Gene: OR2L13 olfactory receptor, family 2, subfamily L, member 13| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene&Cmd=ShowDetailView&TermToSearch=284521| accessdate = }}</ref>
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| }}
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| ==See also== | | == See also == |
| * [[Olfactory receptor]] | | * [[Olfactory receptor]] |
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| ==References== | | == References == |
| {{reflist|2}} | | {{reflist}} |
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| ==Further reading==
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| {{refbegin | 2}}
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| {{PBB_Further_reading
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| | citations =
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| *{{cite journal | author=Strausberg RL, Feingold EA, Grouse LH, ''et al.'' |title=Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. |journal=Proc. Natl. Acad. Sci. U.S.A. |volume=99 |issue= 26 |pages= 16899-903 |year= 2003 |pmid= 12477932 |doi= 10.1073/pnas.242603899 }}
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| *{{cite journal | author=Gerhard DS, Wagner L, Feingold EA, ''et al.'' |title=The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |journal=Genome Res. |volume=14 |issue= 10B |pages= 2121-7 |year= 2004 |pmid= 15489334 |doi= 10.1101/gr.2596504 }}
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| *{{cite journal | author=Gregory SG, Barlow KF, McLay KE, ''et al.'' |title=The DNA sequence and biological annotation of human chromosome 1. |journal=Nature |volume=441 |issue= 7091 |pages= 315-21 |year= 2006 |pmid= 16710414 |doi= 10.1038/nature04727 }}
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| {{refend}}
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| == External links == | | == External links == |
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| {{NLM content}} | | {{NLM content}} |
| {{membrane-protein-stub}} | | {{transmembranereceptor-stub}} |
| {{Olfactory receptors}} | | {{Olfactory receptors}} |
| [[Category:G protein coupled receptors]] | | |
| {{WikiDoc Sources}}
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| | [[Category:Olfactory receptors]] |
Olfactory receptor 2L13 is a protein that in humans is encoded by the OR2L13 gene.[1]
Function
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[1]
See also
References
External links
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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