Growth hormone deficiency laboratory findings

Growth hormone deficiency Microchapters
Home
Patient Information
Overview
Historical Perspective
Classification
Pathophysiology
Causes
Differentiating Growth hormone deficiency from other Diseases
Epidemiology and Demographics
Risk Factors
Screening
Natural History, Complications and Prognosis
Diagnosis
Diagnostic Criteria
History and Symptoms
Physical Examination
Laboratory Findings
X Ray
CT
MRI
Echocardiography or Ultrasound
Other Imaging Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Surgery
Primary Prevention
Secondary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Growth hormone deficiency laboratory findings On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Growth hormone deficiency laboratory findings All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Growth hormone deficiency laboratory findings
CDC on Growth hormone deficiency laboratory findings
Growth hormone deficiency laboratory findings in the news
Blogs on Growth hormone deficiency laboratory findings
Directions to Hospitals Treating Growth hormone deficiency
Risk calculators and risk factors for Growth hormone deficiency laboratory findings

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

Laboratory Findings

• Hypoglycemia
• Jaundice

In children,

• Low levels of IGF1, IGF2, IGF binding protein 3
• Subnormal frequency and amplitude of GH secretory peaks when sampled over several hours
• Subnormal GH secretion in response to at least two provocative stimuli
• Increased IGF1 levels after a few days of GH treatment

In adults,

• Higher cholesterol levels
• Low IGF1 level
• Subnormal frequency and amplitude of GH secretory peaks when tracked over several hours
• Subnormal GH secretion in response to at least two provocative stimuli

Provocative Tests

• "Provocative tests" involve giving a dose of an agent that will normally provoke a pituitary to release a burst of growth hormone. An intravenous line is established, the agent is given, and small amounts of blood are drawn at 15 minute intervals over the next hour to determine if a rise of GH was provoked.
• Agents which have been used clinically to stimulate and assess GH secretion are arginine, levodopa, clonidine, epinephrine and propranolol, glucagon and insulin.

Overview

• An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
• Laboratory findings consistent with the diagnosis of [disease name] include [abnormal test 1], [abnormal test 2], and [abnormal test 3].
• [Test] is usually normal among patients with [disease name].
• Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].

OR

• There are no diagnostic laboratory findings associated with [disease name].

Laboratory Findings

• There are no diagnostic laboratory findings associated with [disease name].

OR

• An elevated/reduced concentration of serum/blood/urinary/CSF/other [lab test] is diagnostic of [disease name].
• [Test] is usually normal among patients with [disease name].
• Laboratory findings consistent with the diagnosis of [disease name] include
  • [abnormal test 1]
  • [abnormal test 2]
  • [abnormal test 3]

• Some patients with [disease name] may have elevated/reduced concentration of [test], which is usually suggestive of [progression/complication].