Antithrombin III deficiency: Difference between revisions
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Revision as of 13:03, 21 September 2012
| Antithrombin III deficiency | |
| ICD-9 | 289.81 |
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| OMIM | 107300 |
| DiseasesDB | 783 |
| MeSH | D020152 |
For patient information click here
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Antithrombin III deficiency Microchapters |
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Differentiating Antithrombin III deficiency from other Diseases |
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Diagnosis |
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Treatment |
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Case Studies |
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Antithrombin III deficiency On the Web |
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American Roentgen Ray Society Images of Antithrombin III deficiency |
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Directions to Hospitals Treating Antithrombin III deficiency |
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Risk calculators and risk factors for Antithrombin III deficiency |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Antithrombin III deficiency is a rare hereditary disorder that generally comes to light when a patient suffers recurrent venous thrombosis and pulmonary embolism.
This was first described by Egeberg in 1965.[1]
The patients are treated with anticoagulants or, more rarely, with antithrombin concentrate.
In renal failure, especially nephrotic syndrome, antithrombin is lost in the urine, leading to a higher activity of Factor II and Factor X and in increased tendency to thrombosis.
Related Chapters
References
- ↑ Egeberg O. Inherited antithrombin deficiency causing thrombophilia. Thromb Diath Haemorrh 1965;13:516–520. PMID 14347873.