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Revision as of 13:33, 17 June 2015

Cryoglobulinemia Microchapters

Home

Patient Information

Overview

Historical Perspective

Classification

Pathophysiology

Causes

Differentiating Cryoglobulinemia from other Diseases

Epidemiology and Demographics

Risk Factors

Screening

Natural History, Complications and Prognosis

Diagnosis

Diagnostic Study of Choice

History and Symptoms

Physical Examination

Laboratory Findings

Electrocardiogram

X Ray

CT

MRI

Ultrasound

Other Imaging Findings

Other Diagnostic Studies

Treatment

Medical Therapy

Surgery

Primary Prevention

Secondary Prevention

Cost-Effectiveness of Therapy

Future or Investigational Therapies

Case Studies

Case #1

Cryoglobulinemia other diagnostic studies On the Web

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MRI

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Risk calculators and risk factors for Cryoglobulinemia other diagnostic studies

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2]

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Overview

Other Diagnostic Studies

Skin Biopsy

Skin biopsy can be of value in establishing the diagnosis.

Renal Biopsy

  • The characteristic findings on renal biopsy are
    1. Intraluminal thrombi
    2. Diffuse IgM deposition in the capillary loops
    3. Subendothelial deposits in a “curvilinear” pattern on EM.
  • Only 14% develop end stage renal disease (ESRD) at 10 years after a renal biopsy demonstrates MC.
  • Recurrent MC can affect up to 70% of transplanted kidneys, but does not preclude transplantation since most of these grafts do not fail.

References


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