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__NOTOC__
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{{Hemophilia}}
{{Hemophilia}}
{{CMG}}
{{CMG}} {{AE}} {{Sab}}


==Overview==
==Overview==
MRI may be helpful in the diagnosis of hemophilia. Findings on MRI suggestive of hemophilic arthropathy include effusion, synovial hyperplasia, erosion, subchondral cyst, cartilage loss, osteonecrosis, fibrocartilage tear, ligament tear, loose body.
==MRI==
==MRI==
([http://www.radswiki.net Images courtesy of RadsWiki])
'''The additive European MRI scoring system'''<ref name="pmid15230954">{{cite journal |vauthors=Lundin B, Pettersson H, Ljung R |title=A new magnetic resonance imaging scoring method for assessment of haemophilic arthropathy |journal=Haemophilia |volume=10 |issue=4 |pages=383–9 |date=July 2004 |pmid=15230954 |doi=10.1111/j.1365-2516.2004.00902.x |url=}}</ref>
{| style="border: 0px; font-size: 90%; margin: 3px; width:400px"
| valign="top" |
|+
! style="background: #4479BA; width: 350px;" | {{fontcolor|#FFF|Type of change}}
! style="background: #4479BA; width: 50px;" | {{fontcolor|#FFF|Score}}
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold |
Subchondral cysts
*Present in at least one bone
*Present in at least two bones
*More than three cysts in at least one bone
*More than three cysts in at least two bones
*Largest size > 4 mm in at least one bone
*Largest size > 4 mm in at least two bones
| style="padding: 5px 5px; background: #F5F5F5;" |
<br>
*1
*1
*1
*1
*1
*1
|-
| style="padding: 5px 5px; background: #DCDCDC;font-weight: bold" align="center" |Enlargement of [[epiphysis]]
| style="padding: 5px 5px; background: #F5F5F5;" |
*Absent = 0
*Present = 1


<gallery>
|-
Image:Hemophilia ankle MRI 104.jpg|Ankle MRI in a patient with Hemophilia
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" |Irregularity of subchondral surface
Image:Hemophilia ankle MRI 105.jpg|Ankle MRI in a patient with Hemophilia
| style="padding: 5px 5px; background: #F5F5F5;" |
</gallery>
*Absent = 0
*Partially involved = 1
*Totally involved = 2
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" |Narrowing of [[joint]] space
| style="padding: 5px 5px; background: #F5F5F5;" |
*Absent = 0
*Joint space > 1 mm = 1
*Joint space < 1 mm = 2
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" |Subchondral [[Cyst|cysts]] formation
| style="padding: 5px 5px; background: #F5F5F5;" |
*Absent = 0
*1 cyst = 1
*>1 cyst = 2
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" |Erosion of [[joint]] margins
| style="padding: 5px 5px; background: #F5F5F5;" |
*Absent = 0
*Present = 1
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" |Gross incongruence of articulating [[bone]] ends
| style="padding: 5px 5px; background: #F5F5F5;" |
*Absent = 0
*Slight = 1
*Pronounced = 2
|-
| style="padding: 5px 5px; background: #DCDCDC; font-weight: bold" align="center" |[[Joint]] deformity (angulation and/or displacement)
| style="padding: 5px 5px; background: #F5F5F5;" |
*Absent = 0
*Slight = 1
*Pronounced = 2
|-
|}


<gallery>
Image:Hemophilia knee MRI 103.jpg|Knee MRI in a patient with Hemophilia
Image:Hemophilia knee MRI 104.jpg|Knee MRI in a patient with Hemophilia
Image:Hemophilia knee MRI 105.jpg|Knee MRI in a patient with Hemophilia
</gallery>


==References==
==References==

Revision as of 23:08, 22 January 2019

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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1] Associate Editor(s)-in-Chief: Sabawoon Mirwais, M.B.B.S, M.D.[2]

Overview

MRI may be helpful in the diagnosis of hemophilia. Findings on MRI suggestive of hemophilic arthropathy include effusion, synovial hyperplasia, erosion, subchondral cyst, cartilage loss, osteonecrosis, fibrocartilage tear, ligament tear, loose body.

MRI

The additive European MRI scoring system[1]

Type of change Score

Subchondral cysts

  • Present in at least one bone
  • Present in at least two bones
  • More than three cysts in at least one bone
  • More than three cysts in at least two bones
  • Largest size > 4 mm in at least one bone
  • Largest size > 4 mm in at least two bones


  • 1
  • 1
  • 1
  • 1
  • 1
  • 1
Enlargement of epiphysis
  • Absent = 0
  • Present = 1
Irregularity of subchondral surface
  • Absent = 0
  • Partially involved = 1
  • Totally involved = 2
Narrowing of joint space
  • Absent = 0
  • Joint space > 1 mm = 1
  • Joint space < 1 mm = 2
Subchondral cysts formation
  • Absent = 0
  • 1 cyst = 1
  • >1 cyst = 2
Erosion of joint margins
  • Absent = 0
  • Present = 1
Gross incongruence of articulating bone ends
  • Absent = 0
  • Slight = 1
  • Pronounced = 2
Joint deformity (angulation and/or displacement)
  • Absent = 0
  • Slight = 1
  • Pronounced = 2


References

  1. ↑ Lundin B, Pettersson H, Ljung R (July 2004). "A new magnetic resonance imaging scoring method for assessment of haemophilic arthropathy". Haemophilia. 10 (4): 383–9. doi:10.1111/j.1365-2516.2004.00902.x. PMID 15230954.

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