Folate deficiency history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
==Symptoms== | ==History and Symptoms== | ||
[[Diarrhea]], [[loss of appetite]], and [[weight loss]] can occur. Additional signs are [[weakness]], sore tongue, [[headache]]s, heart [[palpitation]]s, [[irritability]], and behavioral disorders.<!-- | [[Diarrhea]], [[loss of appetite]], and [[weight loss]] can occur. Additional signs are [[weakness]], sore tongue, [[headache]]s, heart [[palpitation]]s, [[irritability]], and behavioral disorders.<!-- | ||
Revision as of 19:48, 21 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
History and Symptoms
Diarrhea, loss of appetite, and weight loss can occur. Additional signs are weakness, sore tongue, headaches, heart palpitations, irritability, and behavioral disorders.[1]
Women with folate deficiency who become pregnant are more likely to give birth to low birth weight and premature infants, and infants with neural tube defects.
In adults, anemia (Macrocytic, Megaloblastic anemia) is a sign of advanced folate deficiency.
In infants and children, folate deficiency can slow growth rate.
Late studies suggested an involvement in tumorogenesis (especially in colon) through demethylation/hypomethylation of fast replicating tissues.
Some of these symptoms can also result from a variety of medical conditions other than folate deficiency. It is important to have a physician evaluate these symptoms so that appropriate medical care can be given.
References
- ↑ Haslam N and Probert CS. (1998). "An audit of the investigation and treatment of folic acid deficiency". Journal of the Royal Society of Medicine. 91 (2): 72–3. PMID 9602741.