Severe acute respiratory syndrome medical therapy: Difference between revisions
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There is some evidence that some of the more serious damage in SARS is due to the body's own immune system overreacting to the virus. There may be some benefit from using steroids and other immune modulating agents in the treatment of the more acute SARS patients. Research is continuing in this area. | There is some evidence that some of the more serious damage in SARS is due to the body's own immune system overreacting to the virus. There may be some benefit from using steroids and other immune modulating agents in the treatment of the more acute SARS patients. Research is continuing in this area. | ||
In December 2004 it was reported that Chinese researchers had produced a SARS [[vaccine]]. It has been tested on a group of 36 volunteers, 24 of whom developed antibodies against the virus. <ref>[http://www.chinadaily.com.cn/english/doc/2005-01/15/content_409255.htm First SARS vaccine trials a success] [[China Daily]] January 15, 2005</ref> | |||
A 2006 systematic review of all the studies done on the 2003 SARS epidemic found no evidence that antivirals, steroids or other therapies helped patients. A few suggested they caused harm.<ref>[http://medicine.plosjournals.org/perlserv/?request=get-document&doi=10.1371/journal.pmed.0030343 SARS: Systematic Review of Treatment Effects] [[PLoS Medicine]] September 2006 URL Accessed 13 September 2006 </ref> | |||
==References== | ==References== | ||
Revision as of 14:36, 24 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
Antibiotics are ineffective. Treatment of SARS so far has been largely supportive with antipyretics, supplemental oxygen and ventilatory support as needed.
Suspected cases of SARS must be isolated, preferably in negative pressure rooms, with full barrier nursing precautions taken for any necessary contact with these patients.
There was initially anecdotal support for steroids and the antiviral drug ribavirin, but no published evidence has supported this therapy. Many clinicians now suspect that ribavirin is detrimental.
Researchers are currently testing all known antiviral treatments for other diseases including AIDS, hepatitis, influenza and others on the SARS-causing coronavirus.
There is some evidence that some of the more serious damage in SARS is due to the body's own immune system overreacting to the virus. There may be some benefit from using steroids and other immune modulating agents in the treatment of the more acute SARS patients. Research is continuing in this area.
In December 2004 it was reported that Chinese researchers had produced a SARS vaccine. It has been tested on a group of 36 volunteers, 24 of whom developed antibodies against the virus. [1]
A 2006 systematic review of all the studies done on the 2003 SARS epidemic found no evidence that antivirals, steroids or other therapies helped patients. A few suggested they caused harm.[2]
References
- ↑ First SARS vaccine trials a success China Daily January 15, 2005
- ↑ SARS: Systematic Review of Treatment Effects PLoS Medicine September 2006 URL Accessed 13 September 2006