Thrombosis diagnostic evaluation: Difference between revisions
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{{Thrombosis}} | {{Thrombosis}} | ||
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==Diagnostic Evaluation== | ==Diagnostic Evaluation== | ||
====cDNA-PCR Assays for Gene Mutations and Polymorphisms==== | |||
:*4G/5G [[polymorphism]] of the [[plasminogen activator inhibitor]]-1 gene (PAI-1) | :*4G/5G [[polymorphism]] of the [[plasminogen activator inhibitor]]-1 gene (PAI-1) | ||
:*[[Cystathionine beta synthetase]] (CBS) CBS T833C & G919A | :*[[Cystathionine beta synthetase]] (CBS) CBS T833C & G919A | ||
| Line 14: | Line 12: | ||
:*[[Prothrombin]] G20210A | :*[[Prothrombin]] G20210A | ||
====Serologic (blood) Tests==== | |||
:*[[Anticardiolipin antibodies]] (ACLA) IgG and IgM ACLA | :*[[Anticardiolipin antibodies]] (ACLA) IgG and IgM ACLA | ||
:*[[Antithrombin III]] | :*[[Antithrombin III]] | ||
| Line 20: | Line 18: | ||
:*[[Homocysteine]] | :*[[Homocysteine]] | ||
:*[[Lupus anticoagulant]] (LA) | :*[[Lupus anticoagulant]] (LA) | ||
:*[[ | :*[[Protein C]] | ||
:*[[Protein S]] | :*[[Protein S]] | ||
====Evaluation of Hypofibrinolysis==== | |||
:*4G/5G [[polymorphism]] of the [[plasminogen activator inhibitor]]-1 gene ([[PAI-1]])(requires cDNA-PCR assay for gene mutation) | :*4G/5G [[polymorphism]] of the [[plasminogen activator inhibitor]]-1 gene ([[PAI-1]])(requires cDNA-PCR assay for gene mutation) | ||
:*[[Lipoprotein a]] [[Lp(a)]] | :*[[Lipoprotein a]] [[Lp(a)]] | ||
Revision as of 16:28, 27 February 2013
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Thrombosis Microchapters |
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Site of Thrombosis |
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Differentiating Thrombosis from other Diseases |
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Diagnosis |
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Treatment |
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Thrombosis diagnostic evaluation On the Web |
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Risk calculators and risk factors for Thrombosis diagnostic evaluation |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Diagnostic Evaluation
cDNA-PCR Assays for Gene Mutations and Polymorphisms
- 4G/5G polymorphism of the plasminogen activator inhibitor-1 gene (PAI-1)
- Cystathionine beta synthetase (CBS) CBS T833C & G919A
- Factor V Leiden
- Glycoprotein IIIa A1/A2 (platelet glycoprotein)
- Methylenetetrahydrofolate reductase (MTHFR) MTHFR C677T
- Prothrombin G20210A
Serologic (blood) Tests
- Anticardiolipin antibodies (ACLA) IgG and IgM ACLA
- Antithrombin III
- Factor VIII
- Homocysteine
- Lupus anticoagulant (LA)
- Protein C
- Protein S
Evaluation of Hypofibrinolysis
- 4G/5G polymorphism of the plasminogen activator inhibitor-1 gene (PAI-1)(requires cDNA-PCR assay for gene mutation)
- Lipoprotein a Lp(a)