Idiopathic pulmonary fibrosis medical therapy: Difference between revisions
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==Overview== | ==Overview== | ||
==Medical Therapy== | |||
There is currently no consensus on the treatment of IPF. Hence, none of what follows should be taken as specific advice regarding therapy, as the latter is a decision that must be made on a case-by-case basis in individual patients.<ref name="Walter">{{cite journal | last=Walter | first=N | coauthors=Collard HR, Talmadge E. King, Jr. | title=Current perspectives on the treatment of idiopathic pulmonary fibrosis | journal=Proceedings of the American Thoracic Society | volume=3 | issue=4 | pages=330–338 | publisher=American Thoracic Society | month=June |year=2006 | url=http://pats.atsjournals.org/cgi/content/full/3/4/330 | pmid=16738197 | accessdate=2008-03-05 }}</ref> | |||
There is a lack of large, randomized placebo-controlled trials of therapy for IPF. Moreover, many of the earlier studies were based on the hypothesis that IPF is an inflammatory disorder, and hence studied anti-inflammatory agents such as [[corticosteroids]]. Another problem has been that studies conducted prior to the more recent classification of idiopathic interstitial pneumonias failed to distinguish IPF/UIP from NSIP in particular. Hence, many patients with arguably more steroid-responsive diseases were included in earlier studies, confounding the interpretation of their results. | |||
==References== | ==References== | ||
{{reflist|2}} | {{reflist|2}} | ||
Revision as of 19:45, 25 September 2012
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Differentiating Idiopathic pulmonary fibrosis from other Diseases |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Medical Therapy
There is currently no consensus on the treatment of IPF. Hence, none of what follows should be taken as specific advice regarding therapy, as the latter is a decision that must be made on a case-by-case basis in individual patients.[1]
There is a lack of large, randomized placebo-controlled trials of therapy for IPF. Moreover, many of the earlier studies were based on the hypothesis that IPF is an inflammatory disorder, and hence studied anti-inflammatory agents such as corticosteroids. Another problem has been that studies conducted prior to the more recent classification of idiopathic interstitial pneumonias failed to distinguish IPF/UIP from NSIP in particular. Hence, many patients with arguably more steroid-responsive diseases were included in earlier studies, confounding the interpretation of their results.
References
- ↑ Walter, N (2006). "Current perspectives on the treatment of idiopathic pulmonary fibrosis". Proceedings of the American Thoracic Society. American Thoracic Society. 3 (4): 330–338. PMID 16738197. Retrieved 2008-03-05. Unknown parameter
|coauthors=ignored (help); Unknown parameter|month=ignored (help)