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| ==Case Examples==
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| ===Case #1===
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| ====Clinical Summary====
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| This 33-year-old white female was admitted for evaluation of abnormal findings on a chest x-ray. She was asymptomatic and a physical examination revealed no significant abnormalities. Laboratory results indicated hypercalcemia and elevated gamma globulin. Radiographic examination showed enlarged subcarinal, hilar, and right paratracheal lymph nodes. A right paratracheal lymph node was biopsied. Special stains for acid-fast bacilli and fungi were negative and a diagnosis of sarcoidosis was made.
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| ====Histopathological Findings====
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| [http://www.peir.net Images courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology]
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| [[Image:Sarcoidosis lymph node case 001.jpg|left|thumb|400px|This is a low-power photomicrograph of a lymph node. Note the rather pale-pink color of the tissue with dark-staining cells found in only a few scattered areas. These darker cells represent the original lymphocytes of this lymphoid organ.]]
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| [[Image:Sarcoidosis lymph node case 002.jpg|left|thumb|400px|This photomicrograph of lymph node tissue illustrates a paucity of lymphocytes as well as numerous small, pale-staining nodules (arrows) throughout the tissue.]]
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| [[Image:Sarcoidosis lymph node case 003.jpg|left|thumb|400px|This is a photomicrograph of the small nodules (arrows) seen in the previous image. Close examination reveals that they are composed of large macrophages (epithelioid macrophages). These small granulomas form multiple series of reaction centers throughout the lymph node. Note the remaining lymphocytes surrounding the granulomas.]]
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| [[Image:Sarcoidosis lymph node case 004.jpg|left|thumb|400px|This photomicrograph of a single granuloma illustrates the individual macrophages (arrows) which make up the bulk of this tissue. There is an absence of necrosis in the center of the lesions in this case.]]
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| [[Image:Sarcoidosis lymph node case 005.jpg|left|thumb|400px|This is a photomicrograph of a multinucleated giant cell (1). In the center of this foreign body-containing giant cell there is a small asteroid body (2). There is no functional significance to this asteroid body.]]
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| [[Image:Sarcoidosis lymph node case 006.jpg|left|thumb|400px|This is a higher-power photomicrograph of an asteroid body (arrow) inside of a multinucleated giant cell.]]
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| ==See also== | | ==See also== |
For patient information click here
Editor-in-Chief: Philip Marcus, M.D., M.P.H. [1], Division of Pulmonary Medicine
St. Francis Hospital-The Heart Center, Roslyn, NY
Associate Editor-In-Chief: Cafer Zorkun, M.D., Ph.D. [2] and Hilary Womble, M. D.[[3]]
See also
References
External links
Template:WikiDoc Sources
da:Sarkoidose
de:Sarkoidose
eo:Sarkoidozo
eu:Sarkoidosia
he:סרקואידוזיס
lb:Sarkoidos
nl:Sarcoïdose
no:Sarkoidose
nn:sarkoidose
sq:Sarkoidoza
fi:Sarkoidoosi
sv:Sarkoidos
_lymph_node_biopsy.jpg)