Histoplasmosis: Difference between revisions
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==Symptoms== | ==Symptoms== | ||
[[Chest X-ray]] findings are normal in 40-70% of cases.<ref name=Silberberg_2007 /> Chronic histoplasmosis cases can resemble [[tuberculosis]]; disseminated histoplasmosis affects multiple organ systems and is fatal unless treated. | |||
While histoplasmosis is the most common cause of fibrosing [[mediastinitis]], this remains a relatively rare disease. Severe infections can cause [[hepatosplenomegaly]], [[lymphadenopathy]], and adrenal enlargement. Lesions have a tendency to ''calcify'' as they heal. | While histoplasmosis is the most common cause of fibrosing [[mediastinitis]], this remains a relatively rare disease. Severe infections can cause [[hepatosplenomegaly]], [[lymphadenopathy]], and adrenal enlargement. Lesions have a tendency to ''calcify'' as they heal. | ||
Revision as of 15:25, 26 September 2012
| Histoplasmosis | |
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| Histoplasma capsulatum. Methenamine silver stain showing histopathologic changes in histoplasmosis. | |
| ICD-10 | B39 |
| ICD-9 | 115 |
| DiseasesDB | 5925 |
| MedlinePlus | 001082 |
| MeSH | D006660 |
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Histoplasmosis Microchapters |
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Diagnosis |
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Treatment |
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Case Studies |
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Histoplasmosis On the Web |
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American Roentgen Ray Society Images of Histoplasmosis |
For patient information click here
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Synonyms and keywords: Ajellomyces capsulatus; Darling disease; Darling's disease
Overview
Pathogen
Symptoms
Chest X-ray findings are normal in 40-70% of cases.[1] Chronic histoplasmosis cases can resemble tuberculosis; disseminated histoplasmosis affects multiple organ systems and is fatal unless treated.
While histoplasmosis is the most common cause of fibrosing mediastinitis, this remains a relatively rare disease. Severe infections can cause hepatosplenomegaly, lymphadenopathy, and adrenal enlargement. Lesions have a tendency to calcify as they heal.
Ocular histoplasmosis damages the retina of the eyes. Scar tissue is left on the retina which can experience leakage, resulting in a loss of vision not unlike macular degeneration.
Treatment
Prevention
References
Note: The original version of this article is adapted from the U.S. CDC public domain document at http://www.cdc.gov/ncidod/dbmd/diseaseinfo/histoplasmosis_g.htm
External links
- Histoplasmosis Resource Guide from the National Eye Institute (NEI).
- NIOSH - Histoplasmosis - Protecting Workers at Risk
- Fibrosing Mediastinitis