Thin basement membrane disease history and symptoms: Difference between revisions
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==Overview== | ==Overview== | ||
== | ==Biopsy== | ||
A [[needle aspiration biopsy|kidney biopsy]] is the only way to diagnose thin basement membrane disease. It reveals thinning of the [[glomerular basement membrane]] from the normal 300 to 400 nanometers (nm) to 150 to 250 nm. However, a [[needle aspiration biopsy|biopsy]] is rarely done in cases where the patient has isolated [[microscopic hematuria]], normal [[kidney function]], and no [[proteinuria]]. The prognosis is excellent in this setting unless the clinical manifestations progress, as occurs in most males and some females with [[Alport syndrome]] and many patients with [[IgA nephropathy]]. | |||
==References== | ==References== |
Revision as of 18:31, 28 September 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Biopsy
A kidney biopsy is the only way to diagnose thin basement membrane disease. It reveals thinning of the glomerular basement membrane from the normal 300 to 400 nanometers (nm) to 150 to 250 nm. However, a biopsy is rarely done in cases where the patient has isolated microscopic hematuria, normal kidney function, and no proteinuria. The prognosis is excellent in this setting unless the clinical manifestations progress, as occurs in most males and some females with Alport syndrome and many patients with IgA nephropathy.