Hepatorenal syndrome natural history, complications and prognosis: Difference between revisions
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__NOTOC__ | __NOTOC__ | ||
{{Hepatorenal syndrome}} | {{Hepatorenal syndrome}} | ||
{{CMG}}; {{AE}} {{AN}} | |||
{{CMG}} | |||
==Overview== | ==Overview== | ||
==Natural History== | ==Natural History== | ||
==Complications== | ==Complications== | ||
* [[Bleeding]] | * [[Bleeding]] | ||
* Damage to, and failure of, many organ systems ([[multiorgan system failure]]) | * Damage to, and failure of, many organ systems ([[multiorgan system failure]]) | ||
| Line 19: | Line 16: | ||
==Prognosis== | ==Prognosis== | ||
* Type I HRS carries a very poor prognosis, usually of less than 50% over one month. Patients with type I hepatorenal syndrome are usually ill, may have [[low blood pressures]], and may require therapy with [[inotrope]]s, or intravenous drugs to maintain blood pressure. | |||
* Type I HRS carries a very poor prognosis, usually of less than 50% over one month.Patients with type I hepatorenal syndrome are usually ill, may have [[low blood pressures]], and may require therapy with [[inotrope]]s, or intravenous drugs to maintain blood pressure. | |||
* It is typically associated with [[ascites]] that is unresponsive to [[diuretic]] medications, and also carries a poor, if somewhat longer (median survival ~6 months) outlook,<ref>Blendis L, Wong F. The natural history and management of hepatorenal disorders: from pre-ascites to hepatorenal syndrome. ''Clin Med'' 2003 Mar-Apr;3(2):154-9. PMID 12737373</ref> unless the patient undergoes [[liver transplantation]]. | * It is typically associated with [[ascites]] that is unresponsive to [[diuretic]] medications, and also carries a poor, if somewhat longer (median survival ~6 months) outlook,<ref>Blendis L, Wong F. The natural history and management of hepatorenal disorders: from pre-ascites to hepatorenal syndrome. ''Clin Med'' 2003 Mar-Apr;3(2):154-9. PMID 12737373</ref> unless the patient undergoes [[liver transplantation]]. | ||
Revision as of 01:22, 7 January 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aarti Narayan, M.B.B.S [2]
Overview
Natural History
Complications
- Bleeding
- Damage to, and failure of, many organ systems (multiorgan system failure)
- End-stage kidney disease
- Fluid overload with congestive heart failure or pulmonary edema
- Hepatic coma
- Secondary infections
- Death
Prognosis
- Type I HRS carries a very poor prognosis, usually of less than 50% over one month. Patients with type I hepatorenal syndrome are usually ill, may have low blood pressures, and may require therapy with inotropes, or intravenous drugs to maintain blood pressure.
- It is typically associated with ascites that is unresponsive to diuretic medications, and also carries a poor, if somewhat longer (median survival ~6 months) outlook,[1] unless the patient undergoes liver transplantation.
References
- ↑ Blendis L, Wong F. The natural history and management of hepatorenal disorders: from pre-ascites to hepatorenal syndrome. Clin Med 2003 Mar-Apr;3(2):154-9. PMID 12737373