Acute liver failure overview: Difference between revisions
No edit summary |
No edit summary |
||
| Line 3: | Line 3: | ||
{{CMG}} | {{CMG}} | ||
==Overview== | ==Overview== | ||
'''Acute liver failure''' is the appearance of severe complications that occur rapidly after the first signs of liver disease (such as [[jaundice]]), and indicates that the liver has sustained severe damage (loss of function of 80-90% of liver cells). The complications are [[hepatic encephalopathy]] and impaired [[protein synthesis]] (as measured by the levels of [[serum albumin]] and the [[prothrombin time]] in the blood). | '''Acute liver failure''' is the appearance of severe complications that occur rapidly after the first signs of liver disease (such as [[jaundice]]), and indicates that the liver has sustained severe damage (loss of function of 80-90% of liver cells). The complications that can as a result of liver disease and acute liver failure are [[hepatic encephalopathy]] and impaired [[protein synthesis]] (as measured by the levels of [[serum albumin]] and the [[prothrombin time]] in the blood). | ||
'''Definition : ''' Evidence of coagulation abnormality, usually an International Normalized Ratio (INR) > 1.5, and any degree of mental alteration (encephalopathy) in a patient without preexisting cirrhosis and with an illness of <26 weeks duration. <ref name="pmid4908702">{{cite journal |author=Trey C, Davidson CS |title=The management of fulminant hepatic failure |journal=[[Progress in Liver Diseases]] |volume=3 |issue= |pages=282–98 |year=1970 |pmid=4908702 |doi= |url= |accessdate=2012-10-25}}</ref> | '''Definition : ''' Evidence of coagulation abnormality, usually an International Normalized Ratio (INR) > 1.5, and any degree of mental alteration (encephalopathy) in a patient without preexisting cirrhosis and with an illness of <26 weeks duration. <ref name="pmid4908702">{{cite journal |author=Trey C, Davidson CS |title=The management of fulminant hepatic failure |journal=[[Progress in Liver Diseases]] |volume=3 |issue= |pages=282–98 |year=1970 |pmid=4908702 |doi= |url= |accessdate=2012-10-25}}</ref> | ||
Revision as of 17:06, 28 October 2012
|
Acute liver failure Microchapters |
|
Diagnosis |
|---|
|
Treatment |
|
Case Studies |
|
Acute liver failure overview On the Web |
|
American Roentgen Ray Society Images of Acute liver failure overview |
|
Risk calculators and risk factors for Acute liver failure overview |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Acute liver failure is the appearance of severe complications that occur rapidly after the first signs of liver disease (such as jaundice), and indicates that the liver has sustained severe damage (loss of function of 80-90% of liver cells). The complications that can as a result of liver disease and acute liver failure are hepatic encephalopathy and impaired protein synthesis (as measured by the levels of serum albumin and the prothrombin time in the blood).
Definition : Evidence of coagulation abnormality, usually an International Normalized Ratio (INR) > 1.5, and any degree of mental alteration (encephalopathy) in a patient without preexisting cirrhosis and with an illness of <26 weeks duration. [1]
References
- ↑ Trey C, Davidson CS (1970). "The management of fulminant hepatic failure". Progress in Liver Diseases. 3: 282–98. PMID 4908702.
|access-date=requires|url=(help)