Kaposi's sarcoma physical examination: Difference between revisions
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{{Kaposi's sarcoma}} | {{Kaposi's sarcoma}} | ||
==Physical Examination== | ==Physical Examination== | ||
KS [[lesion]]s are nodules or blotches that may be red, purple, brown, or black, and are usually '''papular''' (ie palpable or raised). | KS [[lesion]]s are nodules or blotches that may be red, purple, brown, or black, and are usually '''papular''' (ie palpable or raised). | ||
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They are typically found on the skin, but spread elsewhere is common, especially the mouth, [[gastrointestinal tract]] and [[respiratory tract]]. Growth can range from very slow to explosively fast, and be associated with significant [[mortality]] and [[morbidity]].<ref>{{cite journal |last=Dezube |first=BJ |authorlink= |coauthors= |year=1996 |month=Oct |title=Clinical presentation and natural history of AIDS--related Kaposi's sarcoma |journal=Hematol Oncol Clin North Am |volume=10 |issue=5 |pages=1023-9 |id= |url=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=8880194&dopt=Citation |accessdate= |quote= }}</ref> | They are typically found on the skin, but spread elsewhere is common, especially the mouth, [[gastrointestinal tract]] and [[respiratory tract]]. Growth can range from very slow to explosively fast, and be associated with significant [[mortality]] and [[morbidity]].<ref>{{cite journal |last=Dezube |first=BJ |authorlink= |coauthors= |year=1996 |month=Oct |title=Clinical presentation and natural history of AIDS--related Kaposi's sarcoma |journal=Hematol Oncol Clin North Am |volume=10 |issue=5 |pages=1023-9 |id= |url=http://www.ncbi.nlm.nih.gov/sites/entrez?cmd=Retrieve&db=PubMed&list_uids=8880194&dopt=Citation |accessdate= |quote= }}</ref> | ||
===Skin=== | |||
The skin lesions most commonly affect the lower limbs, face, mouth and [[genitalia]]. The lesions are usually as described above, but may occasionally be [[plaque]] like (often on the soles of the feet) or even involved in skin breakdown with resulting '''fungating''' lesions. | The skin lesions most commonly affect the lower limbs, face, mouth and [[genitalia]]. The lesions are usually as described above, but may occasionally be [[plaque]] like (often on the soles of the feet) or even involved in skin breakdown with resulting '''fungating''' lesions. | ||
Associated swelling may be from either local [[inflammation]] or [[lymphoedema]] (obstruction of local [[lymphatic vessels]] by the lesion). Skin lesions may be quite disfiguring for the sufferer, and a cause of much psychosocial pathology. | Associated swelling may be from either local [[inflammation]] or [[lymphoedema]] (obstruction of local [[lymphatic vessels]] by the lesion). Skin lesions may be quite disfiguring for the sufferer, and a cause of much psychosocial pathology. | ||
===Mouth=== | |||
Is involved in about 30%, and is the initial site in 15% of AIDS related KS. In the mouth, the [[hard palate]] is most frequently affected, followed by the [[gums]] <ref>{{cite journal |last=Nichols |first=CM |authorlink= |coauthors= |year=1993 |month=Nov |title=Treating Kaposi's lesions in the HIV-infected patient. |journal=J Am Dent Assoc |volume=124 |issue=11 |pages=78-84 |id= |url=http://jada.ada.org/cgi/content/abstract/124/11/78 |accessdate= 2007-06-11 |quote= }}</ref>. Lesions in the mouth may be easily damaged by chewing and bleed or suffer secondary infection, and even interfere with eating or speaking. | Is involved in about 30%, and is the initial site in 15% of AIDS related KS. In the mouth, the [[hard palate]] is most frequently affected, followed by the [[gums]] <ref>{{cite journal |last=Nichols |first=CM |authorlink= |coauthors= |year=1993 |month=Nov |title=Treating Kaposi's lesions in the HIV-infected patient. |journal=J Am Dent Assoc |volume=124 |issue=11 |pages=78-84 |id= |url=http://jada.ada.org/cgi/content/abstract/124/11/78 |accessdate= 2007-06-11 |quote= }}</ref>. Lesions in the mouth may be easily damaged by chewing and bleed or suffer secondary infection, and even interfere with eating or speaking. | ||
==References== | ==References== | ||
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[[Category:Gastroenterology]] | [[Category:Gastroenterology]] | ||
[[Category:Infectious disease]] | [[Category:Infectious disease]] | ||
[[Category:Needs content]] | |||
[[Category:Needs | |||
{{WH}} | {{WH}} | ||
{{WS}} | {{WS}} | ||
Revision as of 16:45, 14 December 2012
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
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Physical Examination
KS lesions are nodules or blotches that may be red, purple, brown, or black, and are usually papular (ie palpable or raised).
They are typically found on the skin, but spread elsewhere is common, especially the mouth, gastrointestinal tract and respiratory tract. Growth can range from very slow to explosively fast, and be associated with significant mortality and morbidity.[1]
Skin
The skin lesions most commonly affect the lower limbs, face, mouth and genitalia. The lesions are usually as described above, but may occasionally be plaque like (often on the soles of the feet) or even involved in skin breakdown with resulting fungating lesions. Associated swelling may be from either local inflammation or lymphoedema (obstruction of local lymphatic vessels by the lesion). Skin lesions may be quite disfiguring for the sufferer, and a cause of much psychosocial pathology.
Mouth
Is involved in about 30%, and is the initial site in 15% of AIDS related KS. In the mouth, the hard palate is most frequently affected, followed by the gums [2]. Lesions in the mouth may be easily damaged by chewing and bleed or suffer secondary infection, and even interfere with eating or speaking.
References
- ↑ Dezube, BJ (1996). "Clinical presentation and natural history of AIDS--related Kaposi's sarcoma". Hematol Oncol Clin North Am. 10 (5): 1023–9. Unknown parameter
|month=ignored (help) - ↑ Nichols, CM (1993). "Treating Kaposi's lesions in the HIV-infected patient". J Am Dent Assoc. 124 (11): 78–84. Retrieved 2007-06-11. Unknown parameter
|month=ignored (help)