Shigellosis laboratory findings

Shigellosis Microchapters
Home
Patient Information
Overview
Historical Perspective
Pathophysiology
Classification
Causes
Differentiating Shigellosis from other Diseases
Epidemiology and Demographics
Risk Factors
Natural History, Complications and Prognosis
Diagnosis
History and Symptoms
Physical Examination
Laboratory Findings
Other Diagnostic Studies
Treatment
Medical Therapy
Primary Prevention
Cost-Effectiveness of Therapy
Future or Investigational Therapies
Case Studies
Case #1
Shigellosis laboratory findings On the Web
Most recent articles
Most cited articles
Review articles
CME Programs
Powerpoint slides
Images
American Roentgen Ray Society Images of Shigellosis laboratory findings All Images X-rays Echo & Ultrasound CT Images MRI
Ongoing Trials at Clinical Trials.gov
US National Guidelines Clearinghouse
NICE Guidance
FDA on Shigellosis laboratory findings
CDC on Shigellosis laboratory findings
Shigellosis laboratory findings in the news
Blogs on Shigellosis laboratory findings
Directions to Hospitals Treating Shigellosis
Risk calculators and risk factors for Shigellosis laboratory findings

Overview

The majority of cases with shigellosis have no significant derangements in either blood or stool work-up. Common findings include leukocytosis with left shift on blood examination, and blood and/or mucus in stools on stool examination. Multiple blood and stool cultures may be needed to rule out bacteremia and to obtain antibiotic susceptibility testing, but the majority of cases yield negative cultures.

Shigellosis Laboratory Findings

Blood Examination

Hematology

• Leukocytosis with left shift is common, but leukopenia has also been reported.
• Anemia
• Thrombocytopenia

Electrolytes

• Hyponatremia

Inflammatory Markers

• Elevated blood concentration of C-reactive protein (CRP)
• Elevated blood concentration of erythrocyte sedimentation rate (ESR)

Renal Function

• Azotemia (elevated blood urea nitrogen)
• Elevated concentration of serum creatinine

Liver Function

• Mild elevation in bilirubin
• Positive blood cultures for Shigella

Blood Culture

• Positive blood culture may be positive for Shigella in the minority of cases with bacteremia.

Stool Examination

Stool Analysis

• Fecal blood
• Fecal leukocytes

Microscopic Evaluation

• Microscopic evidence of leukocytosis on stool smear with methylene-blue stain

Stool culture

• Stool cultures may be positive for Shigella in the minority of cases, especially early during the disease.
• Stool samples typically cultured using agars such as: MacConkey, Hektoen enteric, Salmonella-Shigella, Eosin-methylene blue, or xylose-lysine-deoxycholate. Stool cultures typically demonstrate colorless colonies that do not ferment lactose.

References

Template:WikiDoc Sources