Guillain-Barré syndrome epidemiology and demographics: Difference between revisions
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* New-borns and infants have the least risks of development of GBS | * New-borns and infants have the least risks of development of GBS | ||
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* Incidence is similar across different races. | * Incidence is similar across different races. | ||
===Gender=== | ===Gender=== | ||
* It occurs more commonly in males compared to females. Male to female ratio 1.5:1 | * It occurs more commonly in males compared to females. Male to female ratio 1.5:1 | ||
Revision as of 19:09, 5 December 2012
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editors-In-Chief: Priyamvada Singh, MBBS [2]
Overview
Guillain-Barré syndrome (GBS) is an acute, autoimmune, polyradiculoneuropathy affecting the peripheral nervous system, usually triggered by an acute infectious process. The incidence is approximately 1.2 - 3 / 100,000 persons per year across the world. It is commoner in males compared to female and has two peaks (15-35 years and 50-75 years). Incidence is similar across different races.
Epidemiology and Demographics
USA
- It is the commonest cause of acute, flaccid paralysis in USA.
- Incidence- 1.2 - 3 / 100,000 persons [1], [2]
International
- It has been reported all over the world.
- The incidence is around 1.5 - 3 / 100,000 persons
- The antecedence of Campylobacter jejuni is commoner in Japan and other Asian countries. Whereas, in American continents and European nations an antecedence of cytomegalovirus is common.
Age
- Incidence increases with age.
- Bimodal distribution - First peak during 15 - 35 yrs and second during old age [3].
- New-borns and infants have the least risks of development of GBS
Races
- Incidence is similar across different races.
Gender
- It occurs more commonly in males compared to females. Male to female ratio 1.5:1
- The incidence has been found to increase post-partum and decreases during pregnancy [4]
References
- ↑ Day N (1991). "AIDS and insurer discretion". Ohio Medicine : Journal of the Ohio State Medical Association. 87 (5): 226. PMID 1741839. Unknown parameter
|month=ignored (help);|access-date=requires|url=(help) - ↑ Romhányi I (1975). "[Letter: The concept of "caucasian race"]". Orvosi Hetilap (in Hungarian). 116 (41): 2449. PMID 1187127. Unknown parameter
|month=ignored (help);|access-date=requires|url=(help) - ↑ Prevots DR, Sutter RW (1997). "Assessment of Guillain-Barré syndrome mortality and morbidity in the United States: implications for acute flaccid paralysis surveillance". The Journal of Infectious Diseases. 175 Suppl 1: S151–5. PMID 9203708. Retrieved 2012-02-17. Unknown parameter
|month=ignored (help) - ↑ Jiang GX, de Pedro-Cuesta J, Strigård K, Olsson T, Link H (1996). "Pregnancy and Guillain-Barré syndrome: a nationwide register cohort study". Neuroepidemiology. 15 (4): 192–200. PMID 8817501.
|access-date=requires|url=(help)
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