Congenital syphilis historical perspective: Difference between revisions
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== Historical Perspective == | == Historical Perspective == | ||
*Congenital syphilis was first described in an English 17th century in a pediatric textbook. In the past newborns with [[syphilis]] were abandoned by their mothers because of fear of contagion. | |||
Congenital syphilis was first described in an English 17th century in a pediatric textbook. In the past newborns with [[syphilis]] were abandoned by their mothers because of fear of contagion. Sir Jonathan Hutchinson described the triad of notched [[incisors]], interstitial [[keratitis]], and [[eighth cranial nerve]] [[deafness]] as a criterion for diagnosis of congenital syphilis. The condition was well described in the 15th century and has long been recognized as a syndrome transmitted from an infected adult. | *Sir Jonathan Hutchinson described the triad of notched [[incisors]], interstitial [[keratitis]], and [[eighth cranial nerve]] [[deafness]] as a criterion for diagnosis of congenital syphilis. The condition was well described in the 15th century and has long been recognized as a syndrome transmitted from an infected adult. | ||
*In the 19th century congenital syphilis was believed to be transmitted during conception by the father’s sperm, during delivery in the birth canal, or from infected milk or breasts.<ref name="Obladen2013">{{cite journal|last1=Obladen|first1=Michael|title=Curse on Two Generations: A History of Congenital Syphilis|journal=Neonatology|volume=103|issue=4|year=2013|pages=274–280|issn=1661-7819|doi=10.1159/000347107}}</ref> | |||
*In 1905, Schaudinn and Hoffmann identified Spirochaeta pallida. | |||
*Transplacental transmission from an asymptomatic infected mother was first described in 1906.<ref name="urlGuidelines for the Prevention and Control of Congenital Syphilis">{{cite web |url=https://www.cdc.gov/mmwr/preview/mmwrhtml/00026330.htm |title=Guidelines for the Prevention and Control of Congenital Syphilis |format= |work= |accessdate=}}</ref> | |||
*In 1943, Lentz and Ingraham reported penicillin as treatment for congenital syphilis. | |||
*In 2006, the WHO launched a global effort to eliminate congenital syphilis. | |||
== References == | == References == | ||
Revision as of 18:10, 15 February 2017
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]
Overview
Congenital syphilis was first described in an English 17th century in a pediatric textbook. Transplacental transmission from an asymptomatic infected mother was first described in 1906. Sir Jonathan Hutchinson described the triad of notched incisors, interstitial keratitis, and eighth cranial nerve deafness as a criterion for diagnosis of congenital syphilis.
Historical Perspective
- Congenital syphilis was first described in an English 17th century in a pediatric textbook. In the past newborns with syphilis were abandoned by their mothers because of fear of contagion.
- Sir Jonathan Hutchinson described the triad of notched incisors, interstitial keratitis, and eighth cranial nerve deafness as a criterion for diagnosis of congenital syphilis. The condition was well described in the 15th century and has long been recognized as a syndrome transmitted from an infected adult.
- In the 19th century congenital syphilis was believed to be transmitted during conception by the father’s sperm, during delivery in the birth canal, or from infected milk or breasts.[1]
- In 1905, Schaudinn and Hoffmann identified Spirochaeta pallida.
- Transplacental transmission from an asymptomatic infected mother was first described in 1906.[2]
- In 1943, Lentz and Ingraham reported penicillin as treatment for congenital syphilis.
- In 2006, the WHO launched a global effort to eliminate congenital syphilis.
References
- ↑ Obladen, Michael (2013). "Curse on Two Generations: A History of Congenital Syphilis". Neonatology. 103 (4): 274–280. doi:10.1159/000347107. ISSN 1661-7819.
- ↑ "Guidelines for the Prevention and Control of Congenital Syphilis".