Congenital syphilis screening: Difference between revisions

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Revision as of 18:18, 15 February 2017

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Aditya Govindavarjhulla, M.B.B.S. [2]

Overview

Routine screening of newborn serum or umbilical cord blood is not recommended. Serologic testing of the mother’s serum is preferred rather than testing the infant’s serum.

Screening

Effective prevention and detection of congenital syphilis depends on the identification of syphilis in pregnant women and screening is a key component to decrease the incidence of congenital syphilis. The recommendations for screening are as follows:

	Screening Recommendations
Timing of Screening	Test all pregnant women at the first prenatal visit.
Screening Tests	Nontreponemal tests commonly used for initial screening include: Venereal Disease Research Laboratory (VDRL) Rapid Plasma Reagin (RPR) Confirmatory tests include: Fluorescent treponemal antibody absorbed (FTA-ABS) Treponema pallidum particle agglutination (TPPA)
High Risk Population	Most organizations recommend testing high-risk women again during the third trimester and at delivery. Groups at increased risk include: Uninsured women Women living in poverty Sex workers Illicit drug users Those diagnosed with other sexually transmitted diseases (STDs) Other women living in communities with high syphilis morbidity

References

Template:WikiDoc Sources

@@ Line 7: / Line 7: @@
 ==Screening==
-* Newborn serum is not used for serologic tests. Instead, the mother's serum is preferred. <ref name="urlCDC - Diseases Characterized by Genital, Anal, or Perianal Ulcers - 2010 STD Treatment Guidelines">{{cite web |url=http://www.cdc.gov/std/treatment/2010/genital-ulcers.htm#congenital |title=CDC - Diseases Characterized by Genital, Anal, or Perianal Ulcers - 2010 STD Treatment Guidelines |format= |work= |accessdate=2012-12-20}}</ref>
+Effective prevention and detection of congenital syphilis depends on the identification of syphilis in pregnant women and screening is a key component to decrease the incidence of congenital syphilis. The recommendations for screening are as follows:
-* The serologic tests performed on infant serum can be nonreactive if the mother’s serologic test result is of low titer or the mother was infected late in pregnancy.
+{| border="1"
-* Screening can be performed using either a nontreponemal or treponemal test. If either screening test is positive, testing must be performed immediately using the other complimentary test (i.e., nontreponemal test followed by treponemal test or vice-versa).
+|-
-* No infant or mother should leave the hospital unless maternal serologic status has been documented at least once during [[pregnancy]]; in communities and populations in which the risk for congenital syphilis is high, documentation should also occur at delivery.
+!
+!'''Screening Recommendations'''
+|-
+!'''Timing of Screening'''
+|Test all pregnant women at the first prenatal visit.
+|-
+!'''Screening Tests'''
+|
+*Nontreponemal tests commonly used for initial screening include:
+**Venereal Disease Research Laboratory [[(VDRL)]]
+**Rapid Plasma Reagin (RPR)
+*Confirmatory tests include:
+**Fluorescent treponemal antibody absorbed [[(FTA-ABS)]]
+**Treponema pallidum particle agglutination [[(TPPA)]]
+|-
+!'''High Risk Population'''
+|
+*Most organizations recommend testing high-risk women again during the [[third trimester]] and at [[delivery]].<br>Groups at increased risk include:
+**Uninsured women
+**Women living in poverty
+**Sex workers
+**Illicit drug users
+**Those diagnosed with other [[sexually transmitted diseases]] (STDs)
+**Other women living in communities with high [[syphilis]] [[morbidity]]
+|}
 ==References==

Congenital syphilis screening: Difference between revisions

Revision as of 18:18, 15 February 2017

Overview

Screening

References

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