Patent ductus arteriosus overview: Difference between revisions
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Causes of Patent ductus arteriosus is not known. However, increased incidence have been associated with mother's [[rubella]] and [[genetic]] causes | Causes of Patent ductus arteriosus is not known. However, increased incidence have been associated with mother's [[rubella]] and [[genetic]] causes | ||
==Epidemiology and Demographics== | ==Epidemiology and Demographics== | ||
The PDA is commonly found in [[infant]]s and constitutes only 2% of all congenital defects found in adults. The [[incidence] is greater is in children who are born prematurely with history of [[perinatal asphyxia]] and [[infant]]s with [[congenital rubella]]. | The PDA is commonly found in [[infant]]s and constitutes only 2% of all congenital defects found in adults. The [[incidence]] is greater is in children who are born prematurely with history of [[perinatal asphyxia]] and [[infant]]s with [[congenital rubella]]. | ||
==References== | ==References== | ||
Revision as of 15:51, 22 January 2013
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Patent Ductus Arteriosus Microchapters |
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Differentiating Patent Ductus Arteriosus from other Diseases |
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Patent ductus arteriosus overview On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor-In-Chief: Priyamvada Singh, M.B.B.S. [2], Cafer Zorkun, M.D., Ph.D. [3], Assistant Editor-In-Chief: Kristin Feeney, B.S. [4]
Overview
The Patent Ductus Arteriosus, is a remnant of the distal sixth aortic arch and connects the pulmonary artery at the junction of the main pulmonary artery and the origin of the left pulmonary artery to the proximal descending aorta just after the origin of the left subclavian artery.
Patent ductus arteriosus (PDA) is a congenital heart defect when a child's ductus arteriosus fails to close after birth, producing a heart murmur described in 1898 by Gibson as the classic machinery murmur. Normally, the ductus closes within a few hours or days of birth; when it does not, the result is patent ductus arteriosus. This defect is common in premature infants but rare in full-term infants. Symptoms include shortness of breath and cardiac arrhythmia, and may progress to congestive heart failure if left uncorrected.
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Anatomy
Patent ductus arteriosus is a heart condition that is normal but reverses soon after birth. In a persistent PDA, there is an irregular transmission of blood between two of the most important arteries (aorta and pulmonary artery) in close proximity to the heart. Although the ductus arteriosus normally seals off within a few days, in PDA, the newborn's ductus arteriosus does not close, but remains patent.
Pathophysiology
The pathophysiological consequences depend on the size of the defect and the pulmonary vascular resistance.[1]
Causes
Causes of Patent ductus arteriosus is not known. However, increased incidence have been associated with mother's rubella and genetic causes
Epidemiology and Demographics
The PDA is commonly found in infants and constitutes only 2% of all congenital defects found in adults. The incidence is greater is in children who are born prematurely with history of perinatal asphyxia and infants with congenital rubella.
References
- ↑ Giuliani et al, Cardiology: Fundamentals and Practice, Second Edition, Mosby Year Book, Boston, 1991, pp. 1653-1663.