Hematopoiesis lineages: Difference between revisions
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==Lineages== | ==Lineages== | ||
All blood cells are divided into three lineages. | All blood cells are divided into three lineages. | ||
* [[erythrocyte|Erythroid]] cells are the [[oxygen]] carrying [[red blood cells]]. | * [[erythrocyte|Erythroid]] cells are the [[oxygen]] carrying [[red blood cells]]. | ||
* [[Lymphoid]] cells are the cornerstone of the adaptive immune system. They are derived from common lymphoid progenitors. The lymphoid lineage is primarily composed of [[T-cell]]s and [[B-cell]]s. (white blood cells) | * [[Lymphoid]] cells are the cornerstone of the adaptive immune system. They are derived from common lymphoid progenitors. The lymphoid lineage is primarily composed of [[T-cell]]s and [[B-cell]]s. (white blood cells) | ||
* [[Myeloid]] cells, which includes [[granulocyte]]s, [[megakaryocyte]]s, and [[macrophage]]s, are derived from common myeloid progenitors, and are involved in such diverse roles as [[innate immunity]], [[adaptive immunity]], and [[blood clotting]]. | * [[Myeloid]] cells, which includes [[granulocyte]]s, [[megakaryocyte]]s, and [[macrophage]]s, are derived from common myeloid progenitors, and are involved in such diverse roles as [[innate immunity]], [[adaptive immunity]], and [[blood clotting]]. | ||
[[Image:Hematopoiesis simple.jpg|thumb|left|400px|Simple diagram that shows the development of different blood cells from hematopoietic stem cell to mature cells]] | |||
[[Image:Hematopoiesis (human) diagram.png|thumb|left|400px|Comprehensive diagram that shows the development of different blood cells from hematopoietic stem cell to mature cells]] | [[Image:Hematopoiesis (human) diagram.png|thumb|left|400px|Comprehensive diagram that shows the development of different blood cells from hematopoietic stem cell to mature cells]] | ||
Revision as of 17:24, 26 February 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Lineages
All blood cells are divided into three lineages.
- Erythroid cells are the oxygen carrying red blood cells.
- Lymphoid cells are the cornerstone of the adaptive immune system. They are derived from common lymphoid progenitors. The lymphoid lineage is primarily composed of T-cells and B-cells. (white blood cells)
- Myeloid cells, which includes granulocytes, megakaryocytes, and macrophages, are derived from common myeloid progenitors, and are involved in such diverse roles as innate immunity, adaptive immunity, and blood clotting.
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Granulopoiesis
Granulopoiesis (or granulocytopoiesis) is hematopoiesis of granulocytes.
It occurs primarily within bone marrow.
It involves the following stages:
- Pluripotential hemopoietic stem cell
- Myeloblast
- Promyelocyte
- Eosino/neutro/basophilic myelocyte
- Metamyelocyte
- Band cell
- Granulocytes (Eosino/neutro/basophil)