Hematopoiesis locations: Difference between revisions
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==Locations== | |||
In developing embryos, blood formation occurs in aggregates of blood cells in the yolk sac, called [[blood islands]]. As development progresses, blood formation occurs in the [[spleen]], [[liver]] and [[lymph node]]s. When [[bone marrow]] develops, it eventually assumes the task of forming most of the blood cells for the entire organism. However, maturation, activation, and some proliferation of lymphoid cells occurs in secondary lymphoid organs ([[spleen]], [[thymus]], and [[lymph node]]s). While most haematopoiesis in adults occurs in the marrow of the long bones such as the [[femur]]s, it also occurs in spongy bone like [[rib]]s and [[sternum]]). | |||
===Extramedullary=== <!--Extramedullary hematopoiesis redirects here--> | |||
In some cases, the [[liver]], [[thymus]], and [[spleen]] may resume their haematopoietic function, if necessary. This is called ''extramedullary haematopoiesis''. It may cause these organs to increase in size substantially. <ref name=T4> Semester 4 medical lectures at Uppsala University 2008 by Leif Jansson</ref> | |||
===Other vertebrates=== | |||
In some [[vertebrate]]s, haematopoiesis can occur wherever there is a loose [[stroma]] of connective tissue and slow blood supply, such as the [[gut]], [[spleen]], [[kidney]] or [[ovaries]]. |
Revision as of 17:29, 26 February 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Locations
In developing embryos, blood formation occurs in aggregates of blood cells in the yolk sac, called blood islands. As development progresses, blood formation occurs in the spleen, liver and lymph nodes. When bone marrow develops, it eventually assumes the task of forming most of the blood cells for the entire organism. However, maturation, activation, and some proliferation of lymphoid cells occurs in secondary lymphoid organs (spleen, thymus, and lymph nodes). While most haematopoiesis in adults occurs in the marrow of the long bones such as the femurs, it also occurs in spongy bone like ribs and sternum).
Extramedullary
In some cases, the liver, thymus, and spleen may resume their haematopoietic function, if necessary. This is called extramedullary haematopoiesis. It may cause these organs to increase in size substantially. [1]
Other vertebrates
In some vertebrates, haematopoiesis can occur wherever there is a loose stroma of connective tissue and slow blood supply, such as the gut, spleen, kidney or ovaries.
- ↑ Semester 4 medical lectures at Uppsala University 2008 by Leif Jansson