Lactic acidosis classification: Difference between revisions

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Revision as of 12:12, 17 July 2013

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

The Cohen-Woods classification (1976) categorizes causes of lactic acidosis as follows:

Type A: Decreased perfusion or oxygenation
Type B:
- B1: Underlying diseases (sometimes causing type A)
- B2: Medication or intoxication
- B3: Inborn error of metabolism

@@ Line 10: / Line 10: @@
 ** B2: Medication or intoxication
 ** B3: [[Inborn error of metabolism]]
-Lactic acidosis is an underlying process in the development of [[rigor mortis]].  Tissue in the muscles of the deceased resort to anaerobic metabolism in the absence of oxygen and significant amounts of lactic acid are released into the muscle tissue.  This along with the loss of [[adenosine triphosphate|ATP]] causes the muscles to grow stiff.
 ==References==