Crohn's disease laboratory findings: Difference between revisions
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* A [[complete blood count]] may reveal [[anemia]], which may be caused either by blood loss or [[Cyanocobalamin|vitamin B{{ssub|12}}]] deficiency. The latter may be seen with ileitis because vitamin B{{ssub|12}} is absorbed in the [[ileum]].<!-- | * A [[complete blood count]] may reveal [[anemia]], which may be caused either by blood loss or [[Cyanocobalamin|vitamin B{{ssub|12}}]] deficiency. The latter may be seen with ileitis because vitamin B{{ssub|12}} is absorbed in the [[ileum]].<!-- | ||
--><ref name=Goh>{{cite journal | last = Goh | first = Jason | coauthors = C. A. O'Morain | year = 2003 | month = February | title = Review article: nutrition and adult inflammatory bowel disease | journal = Alimentary Pharmacology & Therapeutics | volume = 17 | issue = 3 | pages = 307-20 | doi =10.1046/j.1365-2036.2003.01482.x | id = PMID 12562443 }}</ref><!-- | --><ref name=Goh>{{cite journal | last = Goh | first = Jason | coauthors = C. A. O'Morain | year = 2003 | month = February | title = Review article: nutrition and adult inflammatory bowel disease | journal = Alimentary Pharmacology & Therapeutics | volume = 17 | issue = 3 | pages = 307-20 | doi =10.1046/j.1365-2036.2003.01482.x | id = PMID 12562443 }}</ref><!-- | ||
--> It is also true in | --> It is also true in patients with ilectomy done in response to the complication. Another cause of anemia is anemia of chronic disease, characterized by its microcytic and hypochromic anemia. There are reasons in anemia, including medication in treatment of inflammatory bowel disease like azathioprine that can lead to cytopenia and sulfasalazine, which can also result in folate malabsorption, etc. | ||
* [[Erythrocyte sedimentation rate]], or ESR, and [[C-reactive protein]] measurements can also be useful to gauge the degree of inflammation.<!-- | * [[Erythrocyte sedimentation rate]], or ESR, and [[C-reactive protein]] measurements can also be useful to gauge the degree of inflammation.<!-- | ||
--><ref>{{cite journal | last = Chamouard | first = Patrick | coauthors = Zoe Richert, Nicolas Meyer, Gabriel Rahmi, René Baumann | year = April | month = 2006 | title = Diagnostic Value of C-Reactive Protein for Predicting Activity Level of Crohn's Disease | journal = Clinical Gastroenterology and Hepatology | doi =10.1016/j.cgh.2006.02.003 | id = PMID 16630759 }} Epub ahead of print</ref> | --><ref>{{cite journal | last = Chamouard | first = Patrick | coauthors = Zoe Richert, Nicolas Meyer, Gabriel Rahmi, René Baumann | year = April | month = 2006 | title = Diagnostic Value of C-Reactive Protein for Predicting Activity Level of Crohn's Disease | journal = Clinical Gastroenterology and Hepatology | doi =10.1016/j.cgh.2006.02.003 | id = PMID 16630759 }} Epub ahead of print</ref> | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Laboratory Findings
Electrolyte and Biomarker Studies
- A complete blood count may reveal anemia, which may be caused either by blood loss or [[Cyanocobalamin|vitamin BTemplate:Ssub]] deficiency. The latter may be seen with ileitis because vitamin BTemplate:Ssub is absorbed in the ileum.[1] It is also true in patients with ilectomy done in response to the complication. Another cause of anemia is anemia of chronic disease, characterized by its microcytic and hypochromic anemia. There are reasons in anemia, including medication in treatment of inflammatory bowel disease like azathioprine that can lead to cytopenia and sulfasalazine, which can also result in folate malabsorption, etc.
- Erythrocyte sedimentation rate, or ESR, and C-reactive protein measurements can also be useful to gauge the degree of inflammation.[2]
- Testing for anti-Saccharomyces cerevisiae antibodies (ASCA) and anti-neutrophil cytoplasmic antibodies (ANCA) has been evaluated to identify inflammatory diseases of the intestine[3] and to differentiate Crohn's disease from ulcerative colitis.[4]
References
- ↑ Goh, Jason (2003). "Review article: nutrition and adult inflammatory bowel disease". Alimentary Pharmacology & Therapeutics. 17 (3): 307–20. doi:10.1046/j.1365-2036.2003.01482.x. PMID 12562443. Unknown parameter
|coauthors=ignored (help); Unknown parameter|month=ignored (help) - ↑ Chamouard, Patrick (April). "Diagnostic Value of C-Reactive Protein for Predicting Activity Level of Crohn's Disease". Clinical Gastroenterology and Hepatology. doi:10.1016/j.cgh.2006.02.003. PMID 16630759. Unknown parameter
|coauthors=ignored (help); Unknown parameter|month=ignored (help); Check date values in:|year=(help) Epub ahead of print - ↑ Kaila, B. (2005). "The anti-Saccharomyces cerevisiae antibody assay in a province-wide practice: accurate in identifying cases of Crohn's disease and predicting inflammatory disease". The Canadian Journal of Gastroenterology. 19 (12): 717–21. PMID 16341311. Retrieved 2006-07-02. Unknown parameter
|month=ignored (help); Unknown parameter|coauthors=ignored (help) - ↑ Israeli, E. (2005). "Anti-Saccharomyces cerevisiae and antineutrophil cytoplasmic antibodies as predictors of inflammatory bowel disease". Gut. 54 (9): 1232–6. doi:10.1136/gut.2004.060228. PMID 16099791. Unknown parameter
|coauthors=ignored (help); Unknown parameter|month=ignored (help)