Dyspepsia classification: Difference between revisions
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Revision as of 13:07, 4 June 2015
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Dyspepsia is broadly classified into two major types: ulcer and non-ulcer dyspepsia. The latter is also known as functional dyspepsia.
Classification
Ulcer Dyspepsia
Ulcer dyspepsia accounts to 20-30 % of all dyspepsia cases and is caused by peptic ulcer disease, GERD. Structural disease of the gastrointestinal tract exists in ulcer dyspepsia and hence endoscopy is abnormal.
Non-Ulcer Dyspepsia
Non-ulcer dyspepsia, also called functional dyspepsia (FD), is defined by the Rome III criteria as symptoms of epigastric pain or discomfort (prevalence in FD of 89-90%), postprandial fullness (75-88%), and early satiety (50-82%) within the last 3 months with symptom onset at least 6 months earlier. Patients cannot have any evidence of structural disease to explain symptoms and predominant symptoms of gastroesophageal reflux are exclusionary.[1]
Causes of functional dyspepsia are not clear but researchers have focused on the following factors:
- Gastric motor function
- Visceral sensitivity
- Helicobacter pylori infection
- Psychosocial factors