Leg ulcer: Difference between revisions

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{|style="width:82%; height:100px" border="1"
{|style="width:82%; height:100px" border="1"
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular'''
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | No underlying causes
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Allergic vasculitis]],  [[Anemia]],  [[Aneurysm]],  [[Angiosarcoma]],  [[Arterial dysplasia]],  [[Arterial insufficiency]],  [[Arterial thrombosis]],  [[Arterio-venous malformation]],  [[Arteriovenous fistulas]],  [[Arteriovenous malformation]],  [[Atheroma]],  [[Atherosclerosis]],  [[Cholesterol embolism]],  [[Chronic venous insufficiency]],  [[Churg-strauss syndrome]],  [[Congestive heart failure]],  [[Deep vein thrombosis ]],  [[Dehydration]],  [[Diabetes mellitus]],  [[Embolism]],  [[Heart failure]],  [[Hypertension]],  [[Hypotension]],  [[Hypothermia]],  [[Kaposi's sarcoma]],  [[Leukocytoclastic vasculitis]],  [[Livedoid vasculopathy]],  [[Lymphangitis]],  [[Lymphatic obstruction]],  [[Lymphatic vessel dysplasia]],  [[Lymphedema]],  [[Peripheral artery disease]],  [[Polyarteritis nodosa]],  [[Polyarteritis]],  [[Postthrombotic syndrome]],  [[Raynaud's syndrome]],  [[Sepsis ]],  [[Septic emboli]],  [[Thromboangiitis obliterans]],  [[Thrombotic thrombocytopenic purpura]],  [[Varicose veins]],  [[Vasculitis]],  [[Venous dysplasia]],  [[Wegener's granulomatosis]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Chemical/Poisoning'''
| '''Chemical/Poisoning'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Arsenic]],  [[Erythema induratum of bazin]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Dermatologic'''
| '''Dermatologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Actinic keratosis]],  [[Advanced age]],  [[Allergic vasculitis]],  [[Amoebiasis cutis]],  [[Contact dermatitis]],  [[Continuous trauma]],  [[Crohn's disease]],  [[Decubitus ulcer]],  [[Ecthyma]],  [[Erysipelas]],  [[Erythema induratum of bazin]],  [[Filariasis]],  [[Furuncle]],  [[Glanders]],  [[Herpes simplex]],  [[Incontinence]],  [[Keratoacanthoma]],  [[Lymphoma ulcers]],  [[Madura foot]],  [[Melanoma]],  [[Perforating dermatosis ]],  [[Porphyria cutanea tarda]],  [[Prolonged Immobilization]],  [[Radiation dermatitis]],  [[Sporotrichosis]],  [[Squamous cell carcinoma  ]],  [[Ulcerative colitis]],  [[Xeroderma pigmentosum]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Drug Side Effect'''
| '''Drug Side Effect'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Coumarin]],  [[Ergotamine]],  [[Extravasated cytostatic agents]],  [[Fibrinolysis factors (t-PA, PAI, Plasmin)]],  [[Halogens]],  [[Hydroxyurea]],  [[Leflunomide]],  [[Methotrexate]],  [[Penicillin]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Endocrine'''
| '''Endocrine'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Diabetes mellitus]],  [[Necrobiosis lipoidica]]
|-  
|-  
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Environmental'''
| '''Environmental'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Burns]],  [[Cold injury]],  [[Contact dermatitis]],  [[Heat]],  [[Ionizing radiation]],  [[Noxious chemicals]],  [[Radiation dermatitis]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Gastroenterologic'''
| '''Gastroenterologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Crohn's disease]],  [[Incontinence]],  [[Ulcerative colitis]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Genetic'''
| '''Genetic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Arterial dysplasia]],  [[Factor V Leiden mutation]],  [[Gaucher's disease]],  [[Hereditary spherocytosis]],  [[Klinefelter syndrome]],  [[Leukocyte adhesion deficiency]],  [[Lymphatic vessel dysplasia]],  [[Prolidase deficiency]],  [[Thalassaemia]],  [[Venous dysplasia]],  [[Xeroderma pigmentosum]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Hematologic'''
| '''Hematologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Anemia]],  [[antiphospholipid syndrome]],  [[antithrombin III deficiency]],  [[Blood clot]],  [[Coumarin]],  [[Cryoglobulinemia]],  [[Deep vein thrombosis ]],  [[dysproteinaemia]],  [[Essential thrombocythemia]],  [[Factor V Leiden mutation]],  [[Factor XIII deficiency]],  [[Felty's syndrome]],  [[Fibrinolysis factors (t-PA, PAI, Plasmin)]],  [[granulocytopenia]],  [[hereditary spherocytosis]],  [[Langerhans cell histiocytosis]],  [[Leukemia]],  [[Leukocyte adhesion deficiency]],  [[lupus anticoagulant]],  [[Macroglobulinemia]],  [[Myelodysplasia]],  [[Plasma coagulation inhibitors (antithrombinviii, apc resistance, protein c and s)]],  [[polyclonal dysproteinaemia]],  [[polycythemia ]],  [[Polycythemia vera]],  [[Primary polycythemia]],  [[primary thrombocythemia]],  [[Protein c deficiency]],  [[Protein s deficiency]],  [[purpura]],  [[Sickle cell anemia]],  [[Thalassemia]],  [[thrombotic thrombocytopenic ]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Iatrogenic'''
| '''Iatrogenic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Calcinosis cutis]],  [[Extravasated cytostatic agents]],  [[Radiation dermatitis]],  [[Vaccinations]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Infectious Disease'''
| '''Infectious Disease'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Actinomycosis]],  [[Amoebiasis cutis]],  [[Amoebiasis]],  [[Anthrax]],  [[Bacillary angiomatosis]],  [[Bacterial infection]],  [[Bacteroides]],  [[Blastomycosis]],  [[Borrelia vincenti]],  [[Cellulitis]],  [[Coccidiomycosis]],  [[Cold agglutinin disease]],  [[Diphtheria]],  [[Ecthyma gangrenosum ]],  [[Ecthyma]],  [[Erysipelas]],  [[Fasciitis necroticans ]],  [[Filariasis]],  [[Folliculitis]],  [[Franciscella tularensis]],  [[Furuncle]],  [[Gas gangrene ]],  [[Glanders]],  [[Granuloma inguinale]],  [[hemophilus ducreyi]],  [[Herpes simplex]],  [[Histoplasmosis]],  [[Kala-azar]],  [[Leishmaniasis]],  [[Leprosy]],  [[Lues maligna]],  [[Lymphangitis]],  [[Madura foot]],  [[Mycobacterium ulcerans]],  [[Mycosis fungoides]],  [[Osteomyelitis]],  [[Papillomatosis cutis carcinoides]],  [[Poliomyelitis]],  [[Rodent ulcer]],  [[Sepsis ]],  [[Septic emboli]],  [[Sporotrichosis]],  [[Syphilis]],  [[Tinea pedis]],  [[Tropical ulcer]],  [[Tuberculosis]],  [[Tularemia]],  [[Ulceration pyoderma ]],  [[Variola virus]],  [[Vasculitis]],  [[Yaws]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Musculoskeletal/Orthopedic'''
| '''Musculoskeletal/Orthopedic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Badly united fracture]],  [[Lower limb fractures]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Neurologic'''
| '''Neurologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Alcoholic neuropathy]],  [[Autonomic dysfunction]],  [[Dementia]],  [[Diabetic neuropathy]],  [[Hemiplegia]],  [[Infantile palsy]],  [[Multiple sclerosis]],  [[Neuropathy]],  [[Spina bifida]],  [[Spinal cord injury]],  [[Spinal cord lesions]],  [[Syringomyelia]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Nutritional/Metabolic'''
| '''Nutritional/Metabolic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Calcinosis cutis]],  [[Calciphylaxis]],  [[Gout]],  [[Hyperhomocysteinemia]],  [[Malnutrition]],  [[Necrobiosis lipoidica]],  [[Porphyria cutanea tarda]],  [[Starvation]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Oncologic'''
| '''Oncologic'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Angiosarcoma]],  [[Basal cell carcinoma]],  [[Cold agglutinin disease]],  [[Cutaneous lymphoma]],  [[Leukemia]],  [[Lymphoma ulcers]],  [[Macroglobulinemia]],  [[Marjolin's ulcer]],  [[Melanoma]],  [[Metastatic tumours]],  [[Sarcoma]],  [[Squamous cell carcinoma  ]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Psychiatric'''
| '''Psychiatric'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Delirium]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Renal/Electrolyte'''
| '''Renal/Electrolyte'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Calciphylaxis]],  [[Incontinence]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Trauma'''
| '''Trauma'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Continuous trauma]],  [[Lower limb fractures]],  [[Lower limb nerve injury]],  [[Marjolin's ulcer]],  [[Shearing forces]],  [[Spinal cord injury]]
|-
|-
|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
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|-bgcolor="LightSteelBlue"
|-bgcolor="LightSteelBlue"
| '''Miscellaneous'''
| '''Miscellaneous'''
|bgcolor="Beige"| No underlying causes
|bgcolor="Beige"| [[Amyloidosis]],  [[Artefacts]],  [[Decubitus ulcer]],  [[Factitious ulceration]],  [[Friction]],  [[Low weight]],  [[Marjolin's ulcer]],  [[Moisture in the form of perspiration, feces, or urine]],  [[Papulosis maligna atrophicans]],  [[Prolonged Immobilization]],  [[Sarcoidosis]],  [[Spider bites]]
|-
|-
|}
|}

Revision as of 16:23, 12 July 2013

Leg ulcer
Disseminated Intravascular Coagulation: Gross view of thighs and legs at autopsy ecchymoses with central necrosis and ulceration looks like pyoderma gangrenosum.
Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology

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List of terms related to Leg ulcer

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Vendhan Ramanujam M.B.B.S [2]

Overview

Leg ulcers usually refer to ulcers of the lower leg. The most common cause of leg ulcers is venous insufficiency.

Causes

Common Causes

  • List the most common causes here.

Causes by Organ System

Cardiovascular Allergic vasculitis, Anemia, Aneurysm, Angiosarcoma, Arterial dysplasia, Arterial insufficiency, Arterial thrombosis, Arterio-venous malformation, Arteriovenous fistulas, Arteriovenous malformation, Atheroma, Atherosclerosis, Cholesterol embolism, Chronic venous insufficiency, Churg-strauss syndrome, Congestive heart failure, Deep vein thrombosis , Dehydration, Diabetes mellitus, Embolism, Heart failure, Hypertension, Hypotension, Hypothermia, Kaposi's sarcoma, Leukocytoclastic vasculitis, Livedoid vasculopathy, Lymphangitis, Lymphatic obstruction, Lymphatic vessel dysplasia, Lymphedema, Peripheral artery disease, Polyarteritis nodosa, Polyarteritis, Postthrombotic syndrome, Raynaud's syndrome, Sepsis , Septic emboli, Thromboangiitis obliterans, Thrombotic thrombocytopenic purpura, Varicose veins, Vasculitis, Venous dysplasia, Wegener's granulomatosis
Chemical/Poisoning Arsenic, Erythema induratum of bazin
Dental No underlying causes
Dermatologic Actinic keratosis, Advanced age, Allergic vasculitis, Amoebiasis cutis, Contact dermatitis, Continuous trauma, Crohn's disease, Decubitus ulcer, Ecthyma, Erysipelas, Erythema induratum of bazin, Filariasis, Furuncle, Glanders, Herpes simplex, Incontinence, Keratoacanthoma, Lymphoma ulcers, Madura foot, Melanoma, Perforating dermatosis , Porphyria cutanea tarda, Prolonged Immobilization, Radiation dermatitis, Sporotrichosis, Squamous cell carcinoma , Ulcerative colitis, Xeroderma pigmentosum
Drug Side Effect Coumarin, Ergotamine, Extravasated cytostatic agents, Fibrinolysis factors (t-PA, PAI, Plasmin), Halogens, Hydroxyurea, Leflunomide, Methotrexate, Penicillin
Ear Nose Throat No underlying causes
Endocrine Diabetes mellitus, Necrobiosis lipoidica
Environmental Burns, Cold injury, Contact dermatitis, Heat, Ionizing radiation, Noxious chemicals, Radiation dermatitis
Gastroenterologic Crohn's disease, Incontinence, Ulcerative colitis
Genetic Arterial dysplasia, Factor V Leiden mutation, Gaucher's disease, Hereditary spherocytosis, Klinefelter syndrome, Leukocyte adhesion deficiency, Lymphatic vessel dysplasia, Prolidase deficiency, Thalassaemia, Venous dysplasia, Xeroderma pigmentosum
Hematologic Anemia, antiphospholipid syndrome, antithrombin III deficiency, Blood clot, Coumarin, Cryoglobulinemia, Deep vein thrombosis , dysproteinaemia, Essential thrombocythemia, Factor V Leiden mutation, Factor XIII deficiency, Felty's syndrome, Fibrinolysis factors (t-PA, PAI, Plasmin), granulocytopenia, hereditary spherocytosis, Langerhans cell histiocytosis, Leukemia, Leukocyte adhesion deficiency, lupus anticoagulant, Macroglobulinemia, Myelodysplasia, Plasma coagulation inhibitors (antithrombinviii, apc resistance, protein c and s), polyclonal dysproteinaemia, polycythemia , Polycythemia vera, Primary polycythemia, primary thrombocythemia, Protein c deficiency, Protein s deficiency, purpura, Sickle cell anemia, Thalassemia, thrombotic thrombocytopenic
Iatrogenic Calcinosis cutis, Extravasated cytostatic agents, Radiation dermatitis, Vaccinations
Infectious Disease Actinomycosis, Amoebiasis cutis, Amoebiasis, Anthrax, Bacillary angiomatosis, Bacterial infection, Bacteroides, Blastomycosis, Borrelia vincenti, Cellulitis, Coccidiomycosis, Cold agglutinin disease, Diphtheria, Ecthyma gangrenosum , Ecthyma, Erysipelas, Fasciitis necroticans , Filariasis, Folliculitis, Franciscella tularensis, Furuncle, Gas gangrene , Glanders, Granuloma inguinale, hemophilus ducreyi, Herpes simplex, Histoplasmosis, Kala-azar, Leishmaniasis, Leprosy, Lues maligna, Lymphangitis, Madura foot, Mycobacterium ulcerans, Mycosis fungoides, Osteomyelitis, Papillomatosis cutis carcinoides, Poliomyelitis, Rodent ulcer, Sepsis , Septic emboli, Sporotrichosis, Syphilis, Tinea pedis, Tropical ulcer, Tuberculosis, Tularemia, Ulceration pyoderma , Variola virus, Vasculitis, Yaws
Musculoskeletal/Orthopedic Badly united fracture, Lower limb fractures
Neurologic Alcoholic neuropathy, Autonomic dysfunction, Dementia, Diabetic neuropathy, Hemiplegia, Infantile palsy, Multiple sclerosis, Neuropathy, Spina bifida, Spinal cord injury, Spinal cord lesions, Syringomyelia
Nutritional/Metabolic Calcinosis cutis, Calciphylaxis, Gout, Hyperhomocysteinemia, Malnutrition, Necrobiosis lipoidica, Porphyria cutanea tarda, Starvation
Obstetric/Gynecologic No underlying causes
Oncologic Angiosarcoma, Basal cell carcinoma, Cold agglutinin disease, Cutaneous lymphoma, Leukemia, Lymphoma ulcers, Macroglobulinemia, Marjolin's ulcer, Melanoma, Metastatic tumours, Sarcoma, Squamous cell carcinoma
Ophthalmologic No underlying causes
Overdose/Toxicity No underlying causes
Psychiatric Delirium
Pulmonary No underlying causes
Renal/Electrolyte Calciphylaxis, Incontinence
Rheumatology/Immunology/Allergy No underlying causes
Sexual No underlying causes
Trauma Continuous trauma, Lower limb fractures, Lower limb nerve injury, Marjolin's ulcer, Shearing forces, Spinal cord injury
Urologic No underlying causes
Miscellaneous Amyloidosis, Artefacts, Decubitus ulcer, Factitious ulceration, Friction, Low weight, Marjolin's ulcer, Moisture in the form of perspiration, feces, or urine, Papulosis maligna atrophicans, Prolonged Immobilization, Sarcoidosis, Spider bites

Causes in Alphabetical Order

Differential diagnosis of leg ulcer[1][2]

References

  1. ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
  2. ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X

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