Leg ulcer: Difference between revisions
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|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | |style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | ||
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Allergic vasculitis]], [[anemia]], [[aneurysm]], [[angiosarcoma]], [[fibromuscular dysplasia]], [[arterial insufficiency]], [[arterial thrombosis]], [[arterio-venous malformation]], [[arteriovenous fistula]], [[arteriovenous malformation]], [[atheroma]], [[atherosclerosis]], [[cholesterol embolism]], [[venous insufficiency]], [[Churg-Strauss syndrome]], [[congestive heart failure]], [[deep vein thrombosis]], [[dehydration]], [[diabetes mellitus]], [[embolism]], [[heart failure]], [[hypertension]], [[hypotension]], [[hypothermia]], [[kaposi's sarcoma]], [[leukocytoclastic vasculitis]], [[livedoid vasculopathy]], [[lymphangitis]], [[lymphatic obstruction]], lymphatic vessel | |style="height:100px"; style="width:75%" border="1" bgcolor="Beige" | [[Allergic vasculitis]], [[anemia]], [[aneurysm]], [[angiosarcoma]], [[fibromuscular dysplasia]], [[arterial insufficiency]], [[arterial thrombosis]], [[arterio-venous malformation]], [[arteriovenous fistula]], [[arteriovenous malformation]], [[atheroma]], [[atherosclerosis]], [[cholesterol embolism]], [[venous insufficiency]], [[Churg-Strauss syndrome]], [[congestive heart failure]], [[deep vein thrombosis]], [[dehydration]], [[diabetes mellitus]], [[embolism]], [[heart failure]], [[hypertension]], [[hypotension]], [[hypothermia]], [[kaposi's sarcoma]], [[leukocytoclastic vasculitis]], [[livedoid vasculopathy]], [[lymphangitis]], [[lymphatic obstruction]], [[Lymphedema|lymphatic vessel dysplasia]], [[lymphedema]], [[peripheral artery disease]], [[polyarteritis nodosa]], [[polyarteritis]], [[post-thrombotic syndrome]], [[raynaud's syndrome]], [[sepsis]], [[septic emboli]], [[thromboangiitis obliterans]], [[thrombotic thrombocytopenic purpura]], [[varicose veins]], [[vasculitis]], [[ Chronic Venous insufficiency|venous valvular incompetence]], [[Wegener's granulomatosis]] | ||
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| '''Dermatologic''' | | '''Dermatologic''' | ||
|bgcolor="Beige"| [[ | |bgcolor="Beige"| [[Acquired perforating dermatosis]], [[actinic keratosis]], [[advanced age]], [[allergic vasculitis]], [[Amoebiasis|amebiasis cutis]], [[contact dermatitis]], [[Skin trauma|continuous trauma]], [[Crohn's disease]], [[Lymphoma|Cutaneous lymphoma ulcers]], [[decubitus ulcer]], [[Impetigo | ecthyma]], [[erysipelas]], [[Bazin disease | erythema induratum of bazin]], [[filariasis]], [[furuncle]], [[glanders]], [[herpes simplex]], [[incontinence]], [[keratoacanthoma]], [[Eumycetoma | madura foot]], [[melanoma]], [[porphyria cutanea tarda]], [[Bedsore|prolonged immobilization]], [[radiodermatitis]], [[sporotrichosis]], [[squamous cell carcinoma]], [[ulcerative colitis]], [[xeroderma pigmentosum]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Environmental''' | | '''Environmental''' | ||
|bgcolor="Beige"| [[Burns]], [[cold injury]], [[contact dermatitis]], [[heat]], [[ionizing radiation]], [[radiodermatitis]] | |bgcolor="Beige"| [[Burns]], [[Immersion foot|cold injury]], [[contact dermatitis]], [[heat]], [[ionizing radiation]], [[radiodermatitis]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Genetic''' | | '''Genetic''' | ||
|bgcolor="Beige"| [[Fibromuscular dysplasia]], [[factor V Leiden mutation]], [[gaucher's disease]], [[hereditary spherocytosis]], [[klinefelter syndrome]], [[leukocyte adhesion deficiency]], lymphatic vessel | |bgcolor="Beige"| [[Fibromuscular dysplasia]], [[factor V Leiden mutation]], [[gaucher's disease]], [[hereditary spherocytosis]], [[klinefelter syndrome]], [[leukocyte adhesion deficiency]], [[Lymphedema|lymphatic vessel dysplasia]], [[prolidase deficiency]], [[Leprosy|tap1 mutation]], [[thalassaemia]], [[xeroderma pigmentosum]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Hematologic''' | | '''Hematologic''' | ||
|bgcolor="Beige"| [[Activated protein C resistance]], [[anemia]], [[antiphospholipid syndrome]], [[antithrombin III deficiency]], [[blood clot]], [[cryoglobulinemia]], [[deep vein thrombosis ]], [[dysproteinemia]], [[essential thrombocythemia]], [[factor V Leiden mutation]], [[factor XIII deficiency]], [[felty's syndrome]], [[granulocytopenia]], [[hereditary spherocytosis]], [[langerhans cell histiocytosis]], [[leukemia]], [[leukocyte adhesion deficiency]], [[lupus anticoagulant]], [[macroglobulinemia]], [[myelodysplasia]], [[plasmin]], [[plasminogen activator inhibitor-1]], | |bgcolor="Beige"| [[Activated protein C resistance]], [[anemia]], [[antiphospholipid syndrome]], [[antithrombin III deficiency]], [[blood clot]], [[cryoglobulinemia]], [[deep vein thrombosis ]], [[dysproteinemia]], [[essential thrombocythemia]], [[factor V Leiden mutation]], [[factor XIII deficiency]], [[felty's syndrome]], [[granulocytopenia]], [[hereditary spherocytosis]], [[langerhans cell histiocytosis]], [[leukemia]], [[leukocyte adhesion deficiency]], [[lupus anticoagulant]], [[macroglobulinemia]], [[myelodysplasia]], [[plasmin]], [[plasminogen activator inhibitor-1]],[[Dysproteinemia|polyclonal dysproteinemia]], [[polycythemia]], [[polycythemia vera]], [[Polycythemia vera | primary polycythemia]], [[primary thrombocythemia]], [[protein C deficiency]], [[protein S deficiency]], [[purpura]], [[sickle cell anemia]], [[thalassemia]], [[thrombotic thrombocytopenic purpura]],[[tissue plasminogen activator]] | ||
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| '''Infectious Disease''' | | '''Infectious Disease''' | ||
|bgcolor="Beige"| [[Actinomycosis]], [[amoebiasis]] | |bgcolor="Beige"| [[Actinomycosis]], [[Amoebiasis|amoebiasis cutis]], [[amoebiasis]], [[anthrax]], [[bacillary angiomatosis]], [[bacterial infection]], [[bacteroides]], [[blastomycosis]], [[Borrelia|borrelia vincenti]], [[cellulitis]], [[coccidiomycosis]], [[cold agglutinin disease]], [[diphtheria]], [[ecthyma gangrenosum ]], [[Impetigo | ecthyma]], [[erysipelas]], [[fasciitis necroticans ]], [[filariasis]], [[folliculitis]], [[francisella tularensis]], [[furuncle]], [[gas gangrene ]], [[glanders]], [[granuloma inguinale]], [[haemophilus ducreyi]], [[herpes simplex]], [[histoplasmosis]], [[kala-azar]], [[leishmaniasis]], [[leprosy]], [[Syphilis | lues maligna]], [[lymphangitis]], [[Eumycetoma | madura foot]], [[mycobacterium ulcerans]], [[mycosis fungoides]], [[osteomyelitis]], [[Human papillomavirus|papillomatosis cutis carcinoides]], [[poliomyelitis]], [[rodent ulcer]], [[sepsis ]], [[septic emboli]], [[sporotrichosis]], [[syphilis]], [[tinea pedis]], [[Cutaneous leishmaniasis|tropical ulcer]], [[tuberculosis]], [[tularemia]], [[ulcerative pyoderma]], [[variola virus]], [[vasculitis]], [[yaws]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Musculoskeletal/Orthopedic''' | | '''Musculoskeletal/Orthopedic''' | ||
|bgcolor="Beige"| Badly united | |bgcolor="Beige"| [[bone fractures|Badly united fractures]], [[bone fractures]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Neurologic''' | | '''Neurologic''' | ||
|bgcolor="Beige"| [[Alcoholic neuropathy]], [[autonomic dysfunction]], [[ | |bgcolor="Beige"| [[Alcoholic neuropathy]], [[autonomic dysfunction]], [[cerebral palsy]], [[dementia]], [[diabetic neuropathy]], [[hemiplegia]], [[multiple sclerosis]], [[neuropathy]], [[spina bifida]], [[spinal cord injury]], [[spinal cord lesions]], [[syringomyelia]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Oncologic''' | | '''Oncologic''' | ||
|bgcolor="Beige"| [[Angiosarcoma]], [[basal cell carcinoma]], [[cold agglutinin disease]], [[cutaneous lymphoma]], [[leukemia]], [[macroglobulinemia]], [[marjolin's ulcer]], [[melanoma | |bgcolor="Beige"| [[Angiosarcoma]], [[basal cell carcinoma]], [[cold agglutinin disease]], [[Lymphoma|cutaneous lymphoma ulcers]], [[leukemia]], [[macroglobulinemia]], [[marjolin's ulcer]], [[melanoma]], [[sarcoma]], [[squamous cell carcinoma]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Trauma''' | | '''Trauma''' | ||
|bgcolor="Beige"| | |bgcolor="Beige"| [[Skin trauma|Continuous trauma]], [[bone fractures]], [[Sciatica|lower limb nerve injury]], [[marjolin's ulcer]], [[Physical trauma|shearing forces]], [[spinal cord injury]] | ||
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|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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*[[Alcoholic neuropathy]] | *[[Alcoholic neuropathy]] | ||
*[[Allergic vasculitis]] | *[[Allergic vasculitis]] | ||
*[[Amoebiasis]] | *[[Amoebiasis|Amoebiasis cutis]] | ||
*[[Amoebiasis]] | *[[Amoebiasis]] | ||
*[[Amyloidosis]] | *[[Amyloidosis]] | ||
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*[[Bacterial infection]] | *[[Bacterial infection]] | ||
*[[Bacteroides]] | *[[Bacteroides]] | ||
*Badly united | *[[bone fractures|Badly united fracture]] | ||
*[[Basal cell carcinoma]] | *[[Basal cell carcinoma]] | ||
*[[Behcet disease ]] | *[[Behcet disease ]] | ||
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*[[Blood clot]] | *[[Blood clot]] | ||
*[[Bone fractures]] | *[[Bone fractures]] | ||
*[[Borrelia vincenti]] | *[[Borrelia|Borrelia vincenti]] | ||
*[[Bullous pemphigoid]] | *[[Bullous pemphigoid]] | ||
*[[Burns]] | *[[Burns]] | ||
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*[[Calciphylaxis]] | *[[Calciphylaxis]] | ||
*[[Cellulitis]] | *[[Cellulitis]] | ||
*[[Cerebral palsy]] | |||
*[[Cholesterol embolism]] | *[[Cholesterol embolism]] | ||
*[[Chronically injured or diseased skin]] | *[[Chronically injured or diseased skin]] | ||
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*[[Coccidiomycosis]] | *[[Coccidiomycosis]] | ||
*[[Cold agglutinin disease]] | *[[Cold agglutinin disease]] | ||
*[[Cold injury]] | *[[Immersion foot|Cold injury]] | ||
*[[Congestive heart failure]] | *[[Congestive heart failure]] | ||
*[[Contact dermatitis]] | *[[Contact dermatitis]] | ||
* | *[[Skin trauma|Continuous trauma]] | ||
*[[Coumarin]] | *[[Coumarin]] | ||
*[[Crohn's disease]] | *[[Crohn's disease]] | ||
*[[Cryoglobulinemia]] | *[[Cryoglobulinemia]] | ||
* | *[[Lymphoma|Cutaneous lymphoma ulcers]] | ||
*[[Decubitus ulcer]] | *[[Decubitus ulcer]] | ||
*[[Deep vein thrombosis ]] | *[[Deep vein thrombosis ]] | ||
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*[[Hypothermia]] | *[[Hypothermia]] | ||
*[[Incontinence]] | *[[Incontinence]] | ||
*[[Ionizing radiation]] | *[[Ionizing radiation]] | ||
*[[Kala-azar]] | *[[Kala-azar]] | ||
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*[[Livedoid vasculopathy]] | *[[Livedoid vasculopathy]] | ||
*[[Low weight]] | *[[Low weight]] | ||
*[[Lower limb nerve injury]] | *[[Sciatica|Lower limb nerve injury]] | ||
*[[Syphilis | Lues maligna]] | *[[Syphilis | Lues maligna]] | ||
*[[Lupus anticoagulant]] | *[[Lupus anticoagulant]] | ||
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*[[Lymphangitis]] | *[[Lymphangitis]] | ||
*[[Lymphatic obstruction]] | *[[Lymphatic obstruction]] | ||
*Lymphatic vessel | *[[Lymphedema|Lymphatic vessel dysplasia]] | ||
*[[Lymphedema]] | *[[Lymphedema]] | ||
*[[Macroglobulinemia]] | *[[Macroglobulinemia]] | ||
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*[[Marjolin's ulcer]] | *[[Marjolin's ulcer]] | ||
*[[Melanoma]] | *[[Melanoma]] | ||
*[[Methotrexate]] | *[[Methotrexate]] | ||
*[[Moisture in the form of perspiration, feces, or urine]] | *[[Moisture in the form of perspiration, feces, or urine]] | ||
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*[[Neuropathy]] | *[[Neuropathy]] | ||
*[[Osteomyelitis]] | *[[Osteomyelitis]] | ||
*[[Papillomatosis cutis carcinoides]] | *[[Human papillomavirus|Papillomatosis cutis carcinoides]] | ||
*[[Papulosis maligna atrophicans]] | *[[Papulosis maligna atrophicans]] | ||
*[[Pemphigus vulgaris]] | *[[Pemphigus vulgaris]] | ||
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*[[Polyarteritis nodosa]] | *[[Polyarteritis nodosa]] | ||
*[[Polyarteritis]] | *[[Polyarteritis]] | ||
* | *[[Dysproteinemia|Polyclonal dysproteinemia]] | ||
*[[Polycythemia vera]] | *[[Polycythemia vera]] | ||
*[[Porphyria cutanea tarda]] | *[[Porphyria cutanea tarda]] | ||
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*[[Primary thrombocythemia]] | *[[Primary thrombocythemia]] | ||
*[[Prolidase deficiency]] | *[[Prolidase deficiency]] | ||
*[[Prolonged Immobilization]] | *[[Bedsore|Prolonged Immobilization]] | ||
*[[Protein C deficiency]] | *[[Protein C deficiency]] | ||
*[[Protein S deficiency]] | *[[Protein S deficiency]] | ||
*[[Purpura]] | *[[Purpura]] | ||
*[[Pyoderma gangrenosum]] | *[[Pyoderma gangrenosum]] | ||
* | *[[Radiodermatitis]] | ||
*[[Raynaud's syndrome]] | *[[Raynaud's syndrome]] | ||
*[[Rheumatoid arthritis]] | *[[Rheumatoid arthritis]] | ||
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*[[Sepsis ]] | *[[Sepsis ]] | ||
*[[Septic emboli]] | *[[Septic emboli]] | ||
*[[Shearing forces]] | *[[Physical trauma|Shearing forces]] | ||
*[[Sickle cell anemia]] | *[[Sickle cell anemia]] | ||
*[[Sjogren syndrome]] | *[[Sjogren syndrome]] | ||
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*[[Syringomyelia]] | *[[Syringomyelia]] | ||
*[[Systemic lupus erythematosus]] | *[[Systemic lupus erythematosus]] | ||
*[[Tap1 mutation]] | *[[Leprosy|Tap1 mutation]] | ||
*[[Thalassemia]] | *[[Thalassemia]] | ||
*[[Thromboangiitis obliterans]] | *[[Thromboangiitis obliterans]] | ||
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*[[Tinea pedis]] | *[[Tinea pedis]] | ||
*[[Tissue plasminogen activator]] | *[[Tissue plasminogen activator]] | ||
*[[Tropical ulcer]] | *[[Cutaneous leishmaniasis|Tropical ulcer]] | ||
*[[Tuberculosis]] | *[[Tuberculosis]] | ||
*[[Tularemia]] | *[[Tularemia]] | ||
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*[[Vasculitis]] | *[[Vasculitis]] | ||
*[[Venous insufficiency]] | *[[Venous insufficiency]] | ||
*[[Venous valvular incompetence]] | *[[Chronic Venous insufficiency|Venous valvular incompetence]] | ||
*[[Wegener's granulomatosis]] | *[[Wegener's granulomatosis]] | ||
*[[Xeroderma pigmentosum]] | *[[Xeroderma pigmentosum]] |
Revision as of 17:31, 22 July 2013
Leg ulcer | |
Disseminated Intravascular Coagulation: Gross view of thighs and legs at autopsy ecchymoses with central necrosis and ulceration looks like pyoderma gangrenosum. Image courtesy of Professor Peter Anderson DVM PhD and published with permission © PEIR, University of Alabama at Birmingham, Department of Pathology |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Vendhan Ramanujam M.B.B.S [2]
Overview
Leg ulcers usually refer to ulcers of the lower leg. The most common cause of leg ulcers is venous insufficiency.
Causes
Life Threatening Causes
Common Causes
- Basal Cell Carcinoma
- Decubitus ulcer
- Deep vein thrombosis
- Diabetes mellitus
- Hypertension
- Peripheral artery disease
- Rheumatoid ulcers
- Squamous cell carcinoma
- Thromboangiitis obliterans
- Venous insufficiency
- Vasculitis[1][2]
Causes by Organ System
Causes in Alphabetical Order
Differential Diagnosis of Leg Ulcer
- Anemia
- Arteriosclerosis
- Arteriovenous malformation
- Basal cell carcinoma
- Blastomycosis
- Bullous Disease
- Buerger's disease
- Burns
- Cellulitis
- Coccidiomycosis
- Cold agglutinin disease
- Cold injury
- Congestive heart failure
- Contact dermatitis
- Decubitus ulcer
- Deep vein thrombosis
- Diabetes mellitus
- Diabetic neuropathy
- Drugs
- Ecthyma
- Embolism
- Furuncle
- Gaucher's disease
- Gout
- Histoplasmosis
- Insect bites
- Kaposi's sarcoma
- Leprosy
- Leukemia
- Lymphangitis
- Lymphedema
- Macroglobulinemia
- Malnutrition
- Melanoma
- Metastasis
- Mycosis fungoides
- Osteomyelitis
- Other allergic conditions
- Peripheral vascular disease
- Polyarteritis
- Polycythemia vera
- Protozoan infection
- Protein C deficiency
- Protein S deficiency
- Radiation dermatitis
- Raynaud's syndrome
- Rheumatoid arthritis
- Scleroderma
- Septic emboli
- Sickle cell anemia
- Sporotrichosis
- Squamous cell carcinoma
- Syringomyelia
- Systemic Lupus Erythematosus
- Tabes dorsalis
- Thalassemia
- Trauma
- Tuberculosis
- Venous insufficiency[3][4]
References
- ↑ "Differential diagnosis of leg ulcers - Dissemond - 2006 - JDDG: Journal der Deutschen Dermatologischen Gesellschaft - Wiley Online Library". Retrieved 12 July 2013.
- ↑ "http://www.health.wa.gov.au/woundswest/docs/WPR_Nov09_Atypical_Leg_Ulcers.pdf" (PDF). Retrieved 12 July 2013. External link in
|title=
(help) - ↑ Sailer, Christian, Wasner, Susanne. Differential Diagnosis Pocket. Hermosa Beach, CA: Borm Bruckmeir Publishing LLC, 2002:77 ISBN 1591032016
- ↑ Kahan, Scott, Smith, Ellen G. In A Page: Signs and Symptoms. Malden, Massachusetts: Blackwell Publishing, 2004:68 ISBN 140510368X