Lactic acidosis causes: Difference between revisions
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==Causes== | ==Causes== | ||
===Life Threatening Causes=== | ===Life Threatening Causes=== | ||
*[[Cardiac arrest]] | *[[Cardiac arrest]] | ||
*[[Mesenteric ischemia]] | *[[Mesenteric ischemia]] | ||
*[[Sepsis]] | *[[Sepsis]] | ||
*[[Shock]] | |||
===Common Causes=== | |||
*[[Alcoholism]] | |||
*[[Carbon monoxide poisoning]] | |||
*[[Cyanide poisoning]] | |||
*[[Exercise]] | |||
*[[Grand mal seizure]] | |||
*[[Hypoglycemia]] | |||
*[[Hypoxemia]] | |||
*[[Malignancy]] | |||
*[[Metformin]] | |||
*[[Pheochromocytoma]] | |||
*[[Pulmonary edema]] | |||
*[[Salicylate intoxication]] | |||
*[[Stavudine]] | |||
*[[Zidovudine]] | |||
===Causes by Organ System=== | ===Causes by Organ System=== | ||
{|style="width:80%; height:100px" border="1" | {|style="width:80%; height:100px" border="1" | ||
|style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | |style="height:100px"; style="width:25%" border="1" bgcolor="LightSteelBlue" | '''Cardiovascular''' | ||
|style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |ST Elevation [[Myocardial Infarction]] Complications , [[Shock]] , [[Heart diseases]] , [[Cardiomyopathy ]] , [[Cardiac arrest ]] , [[Beriberi Heart Disease]] , Acute [[pulmonary edema ]] | |style="height:100px"; style="width:75%" border="1" bgcolor="Beige" |ST Elevation [[Myocardial Infarction]] Complications , [[Shock]] , [[Heart diseases]] , [[Cardiomyopathy ]] , [[Cardiac arrest ]] , [[Beriberi Heart Disease]] , Acute [[pulmonary edema]] | ||
|- | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
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| '''Nutritional/Metabolic''' | | '''Nutritional/Metabolic''' | ||
|bgcolor="Beige"|[[Von Gierke Disease ]] , [[Mitochondrial]] toxicity , [[Mitochondrial]] neurogastrointestinal encephalopathy syndrome , [[Mitochondrial myopathy]] , Impaired [[pyruvate]] utilization , [[Coenzyme Q10]] deficiency | |bgcolor="Beige"|[[Von Gierke Disease ]] , [[Mitochondrial]] toxicity , [[Mitochondrial]] neurogastrointestinal encephalopathy syndrome , [[Mitochondrial myopathy]] , Impaired [[pyruvate]] utilization , [[Coenzyme Q10]] deficiency | ||
| | |- | ||
|-bgcolor="LightSteelBlue" | |-bgcolor="LightSteelBlue" | ||
| '''Obstetric/Gynecologic''' | | '''Obstetric/Gynecologic''' |
Revision as of 19:03, 22 July 2013
Lactic acidosis Microchapters |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Causes
Life Threatening Causes
Common Causes
- Alcoholism
- Carbon monoxide poisoning
- Cyanide poisoning
- Exercise
- Grand mal seizure
- Hypoglycemia
- Hypoxemia
- Malignancy
- Metformin
- Pheochromocytoma
- Pulmonary edema
- Salicylate intoxication
- Stavudine
- Zidovudine
Causes by Organ System
Cardiovascular | ST Elevation Myocardial Infarction Complications , Shock , Heart diseases , Cardiomyopathy , Cardiac arrest , Beriberi Heart Disease , Acute pulmonary edema |
Chemical/Poisoning | Isopropyl alcohol , Ethanol , Cyanide intoxication , Crotalidae snake poisoning , Copperhead snake poisoning , Contrast medium , Complications During and Following Cardiac Catheterization, Carbon monoxide poisoning , Alcoholism |
Dental | No underlying causes |
Dermatologic | No underlying causes |
Drug Side Effect | Zalcitabine , Tenofovir , Telbivudine , Succinyl-CoA synthetase deficiency , Stavudine , Phenformin , Paracetamol , Metformin , Linezolid , Lamivudine , Glyburide and Metformin , Entecavir , Emtricitabine , Didanosine , Buformin , Biguanide , Atenolol , Ariboflavinosis , Adefovir , Abacavir , Abacavir |
Ear Nose Throat | No underlying causes |
Endocrine | Pheochromocytoma , Latent autoimmune diabetes , Hypoglycemia , Diabetic nephropathy , Diabetes mellitus |
Environmental | Smoke inhalation |
Gastroenterologic | Short bowel syndrome , Mesenteric ischemia , Liver disease , Intestinal ischaemia , Hepatic failure , Bacterial overgrowth of small intestine , Acute liver failure |
Genetic | Type I Glycogen Storage Disease , Type 1 glycogen storage disease , SCHAD deficiency , Pyruvate dehydrogenase phosphatase deficiency , Pyruvate dehydrogenase deficiency, Pyruvate decarboxylase deficiency, Pyruvate carboxylase deficiency, Pyridoxine-5'-phosphate oxidase deficiency, Myopathy with deficiency of succinate dehydrogenase and aconitase, Mitochondrial genome inherited conditions, Mitochondrial encephalomyopathy -- aminoacidopathy , Mitochondrial DNA depletion syndrome , Mitochondrial aspartyl-tRNA synthetase deficiency , Medium and long chan 3-hydroxyacyl-coenzyme A dehydrogenase deficiency , Malonyl-CoA decarboxylase deficiency, Malonyl-CoA decarboxylase deficiency , Malignant hyperpyrexia, Hydroxyacyl-coa dehydrogenase type 2 deficiency , Holocarboxylase synthase deficiency , GRACILE syndrome ,Glycogenosis type 1b, Glycogenosis type 1a, Glycogen Storage Disease Type I , Glycogen storage disease type 1D , Glycogen storage disease type 1C , Fructose-1,6-bisphosphatase deficiency, , Fructose-1,6-diphosphatase deficiency, Fructose-1-phosphate aldolase deficiency, Fructose intolerance, Dihydrolipoamide dehydrogenase deficiency, Decreased activity of pyruvate dehydrogenase , Decreased activity pyruvate carboxylase , 3-methylglutaconic aciduria, type 4 , 3-Hydroxyisobutyric aciduria, 3-Hydroxyacyl-CoA Dehydrogenase II Deficiency , 17- beta-hydroxysteroid dehydrogenase X deficiency |
Hematologic | Burkitt's lymphoma |
Iatrogenic | No underlying causes |
Infectious Disease | Sepsis , Acquired immune deficiency syndrome |
Musculoskeletal/Orthopedic | No underlying causes |
Neurologic | Subacute necrotising encephalomyelopathy , Grand mal seizure , Ethylmalonic encephalopathy |
Nutritional/Metabolic | Von Gierke Disease , Mitochondrial toxicity , Mitochondrial neurogastrointestinal encephalopathy syndrome , Mitochondrial myopathy , Impaired pyruvate utilization , Coenzyme Q10 deficiency |
Obstetric/Gynecologic | Fetal distress |
Oncologic | Non Hodgkin's lymphoma , Malignancy |
Ophthalmologic | No underlying causes |
Overdose/Toxicity | No underlying causes |
Psychiatric | No underlying causes |
Pulmonary | Severehypoxemia (PO2 <25 to 30 mmHg) , Severe asthma , Respiratory failure , Lung disease - reduced oxygen intake , Hypoxia |
Renal/Electrolyte | Renal failure , Hemofiltration |
Rheumatology/Immunology/Allergy | No underlying causes |
Sexual | No underlying causes |
Trauma | No underlying causes |
Urologic | No underlying causes |
Miscellaneous | Succinic acidemia , Strychnine , Severe exercise , Reye's syndrome , Reduced oxygen utilization , Multiple organ dysfunction , Marked acidemia , Intravenous pyelogram , Idiopathic , Hypothermic shivering , Hypoperfusion , Haemorrhage , Finnish lethal neonatal metabolic syndrome , Decreased oxygen delivery , Cuffed blood sample, Chronic fatigue syndrome , MERRF , MELAS |