Idiopathic interstitial pneumonia differential diagnosis: Difference between revisions
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==Overview== | ==Overview== | ||
Careful and extensive investigations in multiple visits to ensure the idiopathic interstitial pneumonia is accurately diagnosed. :*10 to 20% of patients with IPF have positive rheumatoid factor or positive circulating anti-nuclear antibodies (ANAs), but rarely are titers high. However only the presence of high titers (> 1:160) would suggest the presence of a connective tissue disease . <ref name="Scadding-1967">{{Cite journal | last1 = Scadding | first1 = JG. | last2 = Hinson | first2 = KF. | title = Diffuse fibrosing alveolitis (diffuse interstitial fibrosis of the lungs). Correlation of histology at biopsy with prognosis. | journal = Thorax | volume = 22 | issue = 4 | pages = 291-304 | month = Jul | year = 1967 | doi = | PMID = 6035793 }}</ref> <ref name="Nagaya-1969">{{Cite journal | last1 = Nagaya | first1 = H. | last2 = Buckley | first2 = CE. | last3 = Sieker | first3 = HO. | title = Positive antinuclear factor in patients with unexplained pulmonary fibrosis. | journal = Ann Intern Med | volume = 70 | issue = 6 | pages = 1135-45 | month = Jun | year = 1969 | doi = | PMID = 4892605 }}</ref> <ref name="Nagaya-1972">{{Cite journal | last1 = Nagaya | first1 = H. | last2 = Sieker | first2 = HO. |title = Pathogenetic mechanisms of interstitial pulmonary fibrosis in patients with serum antinuclear factor. A histologic and clinical correlation. |journal = Am J Med | volume = 52 | issue = 1 | pages = 51-62 | month = Jan | year = 1972 | doi = | PMID = 4536709 }}</ref>* | |||
==Differential Diagnosis== | ==Differential Diagnosis== | ||
Revision as of 16:19, 19 November 2013
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Ahmed Zaghw, M.D. [2]
Overview
Careful and extensive investigations in multiple visits to ensure the idiopathic interstitial pneumonia is accurately diagnosed. :*10 to 20% of patients with IPF have positive rheumatoid factor or positive circulating anti-nuclear antibodies (ANAs), but rarely are titers high. However only the presence of high titers (> 1:160) would suggest the presence of a connective tissue disease . [1] [2] [3]*
Differential Diagnosis
- Sarcoidosis
- Hypersensitivity pneumonitis
- Collagen vascular disease
- Human immunodeficiency virus
- Antiphospholipid antibody syndrome
- Chronic obstructive pulmonary disease
- Coalworker's pneumoconiosis
- Drug induced pulmonary toxicity
- Lymphocytic interstitial pneumonia
- Idiopathic pulmonary fibrosis
- Diaphragmatic paralysis
- Primary pulmonary hypertension
- Restrictive lung disease
- Silicosis
References
- ↑ Scadding, JG.; Hinson, KF. (1967). "Diffuse fibrosing alveolitis (diffuse interstitial fibrosis of the lungs). Correlation of histology at biopsy with prognosis". Thorax. 22 (4): 291–304. PMID 6035793. Unknown parameter
|month=ignored (help) - ↑ Nagaya, H.; Buckley, CE.; Sieker, HO. (1969). "Positive antinuclear factor in patients with unexplained pulmonary fibrosis". Ann Intern Med. 70 (6): 1135–45. PMID 4892605. Unknown parameter
|month=ignored (help) - ↑ Nagaya, H.; Sieker, HO. (1972). "Pathogenetic mechanisms of interstitial pulmonary fibrosis in patients with serum antinuclear factor. A histologic and clinical correlation". Am J Med. 52 (1): 51–62. PMID 4536709. Unknown parameter
|month=ignored (help)