Niclosamide: Difference between revisions
Gerald Chi (talk | contribs) mNo edit summary |
Gerald Chi (talk | contribs) mNo edit summary |
||
| Line 5: | Line 5: | ||
==Overview== | ==Overview== | ||
Niclosamide is a teniacide ("tenia-" referring to [[tapeworm]]) in the [[anthelmintic]] family especially effective against [[cestodes]] that infect humans. | |||
It is stressed that while anthelmintics are a drug familiy used to treat worm infections, Niclosamide is used specifically to treat [[tapeworms]] and is not effective against worms such as [[pinworms]] or [[roundworms]]. | It is stressed that while anthelmintics are a drug familiy used to treat worm infections, Niclosamide is used specifically to treat [[tapeworms]] and is not effective against worms such as [[pinworms]] or [[roundworms]]. | ||
| Line 38: | Line 38: | ||
==Mechanism of Action== | ==Mechanism of Action== | ||
Niclosamide uncouples oxidative phosphorylation in the tapeworm.<ref name="pmid">{{cite journal |author=Weinbach EC, Garbus J |title=Mechanism of action of reagents that uncouple oxidative phosphorylation|journal=Nature |volume=221 |issue=5185 |pages=1016–8 |year=1969 |pmid= |doi=}}</ref> | |||
==References== | ==References== | ||
Revision as of 20:58, 6 January 2014
| Niclosamide |
|---|
| YOMESAN® Package Insert |
| Clinical Pharmacology |
| Indications |
| Contraindications |
| Side Effects |
| Overdosage |
| Dosage |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Niclosamide is a teniacide ("tenia-" referring to tapeworm) in the anthelmintic family especially effective against cestodes that infect humans.
It is stressed that while anthelmintics are a drug familiy used to treat worm infections, Niclosamide is used specifically to treat tapeworms and is not effective against worms such as pinworms or roundworms.
It is a chewable tablet taken orally, dosage depending on type of worm and patient's age and/or weight.
Niclosamide molecules are lethal to tapeworms upon contact.
Category
Anthelmintic
US Brand Names
NICLOCIDE, YOMESAN (DISCONTINUED)
FDA Package Insert
Description | Clinical Pharmacology | Microbiology | Indications and Usage | Contraindications | Warnings and Precautions | Adverse Reactions | Drug Interactions | Overdosage | Clinical Studies | Dosage and Administration | How Supplied | Labels and Packages
Mechanism of Action
Niclosamide uncouples oxidative phosphorylation in the tapeworm.[1]
References
- ↑ Weinbach EC, Garbus J (1969). "Mechanism of action of reagents that uncouple oxidative phosphorylation". Nature. 221 (5185): 1016–8.