Creutzfeldt-Jakob disease differential diagnosis: Difference between revisions
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==Differential Diagnosis of Creutzfeldt-Jakob Disease== | ==Differential Diagnosis of Creutzfeldt-Jakob Disease== | ||
CJD should be differentiated from variant Creutzfeldt-Jakob disease and Mad Cow disease. Other diseases it should be differentiated from are: | |||
===Neurodegenerative Diseases=== | ===Neurodegenerative Diseases=== | ||
* [[Alzheimer disease]] | * [[Alzheimer disease]] | ||
Revision as of 21:51, 13 February 2014
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Overview
Early signs of Creutzfeldt-Jakob disease(CJD) are highly variable, due to which it is often misdiagnosed or diagnosis is delayed. It should be differentiated from other causes of rapidly progressive dementia such as other neurodegenerative diseases, infections and dementia due to metabolic or toxic etiology.[1]
Differential Diagnosis of Creutzfeldt-Jakob Disease
CJD should be differentiated from variant Creutzfeldt-Jakob disease and Mad Cow disease. Other diseases it should be differentiated from are:
Neurodegenerative Diseases
- Alzheimer disease
- Dementia with Lewy bodies
- Frontotemporal dementia
- Corticobasal degeneration
- Normal pressure hydrocephalus
- Parkinsonian disorder
Autoimmune diseases
Infections
- Encephalitis
- Whipple disease
- Rabies
- Herpes simplex virus
- Postinfectious syndrome
Toxic or metabolic causes
- Vitamin B12 deficiency
- Hypothyroidism
- Side effects of drugs
- Wernicke-Korsakoff syndrome
- Urinary tract infection[1]
References
- ↑ 1.0 1.1 Paterson RW, Torres-Chae CC, Kuo AL, Ando T, Nguyen EA, Wong K; et al. (2012). "Differential diagnosis of jakob-creutzfeldt disease". Arch Neurol. 69 (12): 1578–82. doi:10.1001/2013.jamaneurol.79. PMID 23229042.