Chorioamnionitis pathophysiology: Difference between revisions
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Chorioamnionitis is an [[inflammation]] of the [[chorion]] and [[amnion]]. It is usually caused by a [[bacterial infection]]. | Chorioamnionitis is an [[inflammation]] of the [[chorion]] and [[amnion]]. It is usually caused by a [[bacterial infection]]. | ||
===Mechanisms=== | ===Mechanisms=== | ||
*Ascending bacteria from the lower genital tract (vagina, cervix) which is the most common cause. | *Ascending bacteria from the lower genital tract (vagina, cervix) which is the most common cause. | ||
*Prolonged rupture of the membranes which facilitates the bacteria to invade the maternal tissues. | *Prolonged rupture of the membranes which facilitates the bacteria to invade the maternal tissues. | ||
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Pathophysiology
The amniotic sac consists of two membranes:
- The outer membrane, the chorion, contains the amnion and is part of the placenta.
- The inner membrane, the amnion, contains the amniotic fluid and the fetus.
Chorioamnionitis is an inflammation of the chorion and amnion. It is usually caused by a bacterial infection.
Mechanisms
- Ascending bacteria from the lower genital tract (vagina, cervix) which is the most common cause.
- Prolonged rupture of the membranes which facilitates the bacteria to invade the maternal tissues.
- Invasive fetal procedures (amniocentesis, chorionic villous sampling)
- Haematgenous spread, but it is less common.