Clostridium difficile infection future or investigational therapies: Difference between revisions

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Revision as of 16:45, 24 April 2015

Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]

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 == Future or Investigational Therapies ==
-On December 14, 2005, researchers at McGill University in Montreal, Quebec, led by Dr. Ken Dewar and Dr. Andre Dascal and in collaboration with province-organized NPO Genome Quebec's research facility, announced they had cracked the genetic code of the highly virulent Quebec strain of ''C. difficile''. This was accomplished by using ultra high-throughput sequencing technology. The tests involved doing 400,000 DNA parallel sequencing reactions which took the bacterium's genome apart and reassembled it so it could be studied.<ref name=Loo_2005>{{cite journal |author=Loo V, Poirier L, Miller M, Oughton M, Libman M, Michaud S, Bourgault A, Nguyen T, Frenette C, Kelly M, Vibien A, Brassard P, Fenn S, Dewar K, Hudson T, Horn R, René P, Monczak Y, Dascal A |title=A predominantly clonal multi-institutional outbreak of Clostridium difficile-associated diarrhea with high morbidity and mortality |journal=N Engl J Med |volume=353 |issue=23 |pages=2442-9 |year=2005 |pmid=16322602}}</ref><ref>[http://www.iapm.ca/newsmanager/anmviewer.asp?a=144&z=14 Scientists map C. difficile strain] - Institute of Public Affairs, Montreal</ref>
-It is expected this will allow quicker detection of the disease and better treatment.
 ==References==