Ebola medical therapy: Difference between revisions
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{{CMG}}; {{AE}} {{GRN}} | {{CMG}}; {{AE}} {{GRN}} | ||
==Overview== | ==Overview== | ||
The treatment of Ebola infection is primarily supportive and includes maintaining [[fluids]] and [[electrolytes]], [[homeostasis]], adequate [[oxygen]] levels and [[blood pressure]] and treating any complicating superimposed [[infections]].<ref name=CDC>{{cite web | title = CDC Ebola Hemorrhagic Fever Information Packet | url = http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/Fact_Sheets/Ebola_Fact_Booklet.pdf | year = April 2010 }}</ref> All patients with a confirmed or suspected [[viral hemorrhagic fever]] should be put in isolation with adequate contact precautions.<ref name="pmid21084112">{{cite journal| author=Feldmann H, Geisbert TW| title=Ebola haemorrhagic fever. | journal=Lancet | year= 2011 | volume= 377 | issue= 9768 | pages= 849-62 | pmid=21084112 | doi=10.1016/S0140-6736(10)60667-8 | pmc=PMC3406178 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21084112 }} </ref> No vaccine is currently available. | The treatment of Ebola infection is primarily supportive and includes maintaining [[fluids]] and [[electrolytes]], [[homeostasis]], adequate [[oxygen]] levels and [[blood pressure]] and treating any complicating superimposed [[infections]].<ref name=CDC>{{cite web | title = CDC Ebola Hemorrhagic Fever Information Packet | url = http://www.cdc.gov/ncidod/dvrd/spb/mnpages/dispages/Fact_Sheets/Ebola_Fact_Booklet.pdf | year = April 2010 }}</ref> All patients with a confirmed or suspected [[viral hemorrhagic fever]] should be put in isolation with adequate contact precautions.<ref name="pmid21084112">{{cite journal| author=Feldmann H, Geisbert TW| title=Ebola haemorrhagic fever. | journal=Lancet | year= 2011 | volume= 377 | issue= 9768 | pages= 849-62 | pmid=21084112 | doi=10.1016/S0140-6736(10)60667-8 | pmc=PMC3406178 | url=http://www.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pubmed&tool=sumsearch.org/cite&retmode=ref&cmd=prlinks&id=21084112 }} </ref> No vaccine is currently available. | ||
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The appropriate treatment of shock depends upon the underlying cause. | The appropriate treatment of shock depends upon the underlying cause. | ||
====Bleeding==== | ====Bleeding==== | ||
Replete [[coagulation factors]] with [[fresh frozen plasma]] if available, and [[transfuse]] with packed red blood cells and platelets as needed. Invasive procedures should be avoided to prevent further bleeding. | Replete [[coagulation factors]] with [[fresh frozen plasma]] if available, and [[transfusion|transfuse]] with packed red blood cells and platelets as needed. Invasive procedures should be avoided to prevent further bleeding. | ||
====Dehydration==== | ====Dehydration==== | ||
Replete with intravenous fluids that include electrolyte repletion | Replete with intravenous fluids that include electrolyte repletion |
Revision as of 22:10, 17 July 2014
Ebola Microchapters |
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Ebola medical therapy On the Web |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Guillermo Rodriguez Nava, M.D. [2]
Overview
The treatment of Ebola infection is primarily supportive and includes maintaining fluids and electrolytes, homeostasis, adequate oxygen levels and blood pressure and treating any complicating superimposed infections.[1] All patients with a confirmed or suspected viral hemorrhagic fever should be put in isolation with adequate contact precautions.[2] No vaccine is currently available.
Medical Therapy
Treatment is primarily supportive.
Shock
The appropriate treatment of shock depends upon the underlying cause.
Bleeding
Replete coagulation factors with fresh frozen plasma if available, and transfuse with packed red blood cells and platelets as needed. Invasive procedures should be avoided to prevent further bleeding.
Dehydration
Replete with intravenous fluids that include electrolyte repletion
Vasodilation
Treat with vasopressors
Hypoxia
Treat with supplemental oxygen including intubation as needed.
Superimposed Infections
Treating any complicating infections with empiric antibiotics.
References
- ↑ "CDC Ebola Hemorrhagic Fever Information Packet" (PDF). April 2010.
- ↑ Feldmann H, Geisbert TW (2011). "Ebola haemorrhagic fever". Lancet. 377 (9768): 849–62. doi:10.1016/S0140-6736(10)60667-8. PMC 3406178. PMID 21084112.