Anthrax laboratory findings: Difference between revisions
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| style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Gram Stain]], [[Cell cultures|Cultures]], Toxic Assays''' | | style="background: #F5F5F5; padding: 5px; text-align: center;"| '''[[Gram Stain]], [[Cell cultures|Cultures]], Toxic Assays''' | ||
| style="background: #DCDCDC; padding: 5px;"| [[Blood]]<br>[[Serum]]<br>[[CSF]]<br>[[Pleural fluid]]<br>[[Ascites]]<br>Wound [[exudate]]<br>[[Bronchial]] [[exudate]] | | style="background: #DCDCDC; padding: 5px;"| [[Blood]]<br>[[Serum]]<br>[[CSF]]<br>[[Pleural fluid]]<br>[[Ascites]]<br>Wound [[exudate]]<br>[[Bronchial]] [[exudate]] | ||
| style="background: #DCDCDC; padding: 5px;"| [[]] | | style="background: #DCDCDC; padding: 5px;"| Cultures usually negative after [[antibiotics]]<br>[[Toxins]] may be detected | ||
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Revision as of 23:28, 16 July 2014
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Anthrax Microchapters |
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Diagnosis |
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Case Studies |
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Anthrax laboratory findings On the Web |
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American Roentgen Ray Society Images of Anthrax laboratory findings |
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Risk calculators and risk factors for Anthrax laboratory findings |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Laboratory Findings
The following tests are used in the diagnosis and monitoring of systemic anthrax:[1]
| Test | Initial Findings | Serial Monitoring |
|---|---|---|
| CBC | Hemoconcentration Possible Thrombocytopenia Leukocyte count commonly normal |
Anemia Thrombocytopenia Leukocytosis (late in disease) |
| Electrolyte, Renal Panel, Lactate Level | Decreased Na+ level Increased BUN |
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| Liver Enzymes, Serum Albumin | Elevated transaminase levels hypoalbuminemia |
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| PT, PTT, D-dimer, Fibrinogen | Normal PT/PTT does not exclude DIC or coagulopathy | Low threshold for hypercoagulability workup: Haptoglobin LDH Fibrin split products ADAMTS 13 if hemolytic anemia |
| C-Reactive Protein | Characterization of Inflammatory Response Typically low CRP in injection anthrax |
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| Gram Stain, Cultures, Toxic Assays | Blood Serum CSF Pleural fluid Ascites Wound exudate Bronchial exudate |
Cultures usually negative after antibiotics Toxins may be detected |
References
- ↑ Hendricks, Katherine A.; Wright, Mary E.; Shadomy, Sean V.; Bradley, John S.; Morrow, Meredith G.; Pavia, Andy T.; Rubinstein, Ethan; Holty, Jon-Erik C.; Messonnier, Nancy E.; Smith, Theresa L.; Pesik, Nicki; Treadwell, Tracee A.; Bower, William A. (2014). "Centers for Disease Control and Prevention Expert Panel Meetings on Prevention and Treatment of Anthrax in Adults". Emerging Infectious Diseases. 20 (2). doi:10.3201/eid2002.130687. ISSN 1080-6040.