Phenprocoumon: Difference between revisions
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==Overview== | |||
'''Phenprocoumon''' (marketed under the brand names '''Marcoumar''', '''Marcumar''' and '''Falithrom''') is a long-acting oral [[anticoagulant]] drug, a derivative of [[coumarin]]. It is a [[vitamin K antagonist]] that inhibits coagulation by blocking synthesis of [[coagulation factor]]s II, VII, IX and X. It is used for the [[prophylaxis]] and treatment of thromboembolic disorders ([[thrombosis]]/[[pulmonary embolism]]). It is the standard coumarin used in Germany. | |||
Phenprocoumon is a [[4-hydroxycoumarin]] and inhibits [[vitamin K epoxide reductase]].<ref>[http://www.pharmgkb.org/drug/PA450921#tabview=tab2&subtab=31 Phenprocoumon] at PharmGKB</ref> | |||
==External Links== | |||
==External | |||
* {{DiseasesDB|29943}} | * {{DiseasesDB|29943}} | ||
==References== | |||
{{reflist|2}} | |||
{{Antithrombotics}} | {{Antithrombotics}} | ||
[[Category:Drug]] | [[Category:Drug]] | ||
[[Category: | [[Category:Cardiovascular Drugs]] | ||
[[Category: | [[Category:Anticoagulants]] | ||
Latest revision as of 00:34, 26 July 2014
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| Pharmacokinetic data | |
| Protein binding | 99% |
| Metabolism | hepatic to inactive metabolites |
| Elimination half-life | 5 to 6 days |
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| E number | {{#property:P628}} |
| ECHA InfoCard | {{#property:P2566}}Lua error in Module:EditAtWikidata at line 36: attempt to index field 'wikibase' (a nil value). |
| Chemical and physical data | |
| Formula | C18H16O3 |
| Molar mass | 280.318 g/mol |
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Most recent articles on Phenprocoumon Most cited articles on Phenprocoumon |
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Powerpoint slides on Phenprocoumon |
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Evidence Based Medicine |
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Ongoing Trials on Phenprocoumon at Clinical Trials.gov Trial results on Phenprocoumon Clinical Trials on Phenprocoumon at Google
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US National Guidelines Clearinghouse on Phenprocoumon NICE Guidance on Phenprocoumon
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Definitions |
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Patient resources on Phenprocoumon Discussion groups on Phenprocoumon Patient Handouts on Phenprocoumon Directions to Hospitals Treating Phenprocoumon Risk calculators and risk factors for Phenprocoumon
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Causes & Risk Factors for Phenprocoumon |
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Continuing Medical Education (CME) |
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Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]
Overview
Phenprocoumon (marketed under the brand names Marcoumar, Marcumar and Falithrom) is a long-acting oral anticoagulant drug, a derivative of coumarin. It is a vitamin K antagonist that inhibits coagulation by blocking synthesis of coagulation factors II, VII, IX and X. It is used for the prophylaxis and treatment of thromboembolic disorders (thrombosis/pulmonary embolism). It is the standard coumarin used in Germany.
Phenprocoumon is a 4-hydroxycoumarin and inhibits vitamin K epoxide reductase.[1]
External Links
References
- ↑ Phenprocoumon at PharmGKB
- Pages with script errors
- E number from Wikidata
- ECHA InfoCard ID from Wikidata
- Articles without EBI source
- Chemical pages without ChemSpiderID
- Articles without KEGG source
- Articles without InChI source
- Articles without UNII source
- Drugs with no legal status
- Articles containing unverified chemical infoboxes
- Drug
- Cardiovascular Drugs
- Anticoagulants