Group B streptococcal infection future or investigational therapies: Difference between revisions
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==Overview== | ==Overview== | ||
There is no Group B streptococcus (GBS) [[vaccine]] currently available to help mothers protect their newborns from GBS disease. Researchers are working on developing a vaccine, which may become available one day in the future. Phase I and II clinical trials among healthy, | There is no Group B streptococcus (GBS) [[vaccine]] currently available to help mothers protect their newborns from GBS disease. Researchers are working on developing a vaccine, which may become available one day in the future. Phase I and II clinical trials among healthy, non-pregnant adults of monovalent polysaccharide-protein conjugate [[vaccine]]s of GBS disease-associated types have shown these vaccines to be well tolerated and immunogenic. A recent, double-blind randomized trial of a conjugate vaccine against GBS serotype III among non-pregnant women of reproductive age found a significant delay in acquisition of colonization with the [[vaccine]]-serotype among vaccine recipients.<ref name=CDCMMWR>Verani J.R., McGee L, and Schrag S.J. Prevention of Perinatal Group B Streptococcal Disease. Revised Guidelines from CDC, 2010.[http://www.cdc.gov/mmwr/preview/mmwrhtml/rr5910a1.htm?s_cid=rr5910a1_w CDC.gov]</ref> | ||
==References== | ==References== | ||
Revision as of 14:58, 21 August 2014
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Group B Streptococcal Infection Microchapters |
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Differentiating Group B Streptococcal Infection from other Diseases |
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Diagnosis |
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Group B streptococcal infection future or investigational therapies On the Web |
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Directions to Hospitals Treating Group B streptococcal infection |
Editor-In-Chief: C. Michael Gibson, M.S., M.D. [1]; Associate Editor(s)-in-Chief: Rim Halaby, M.D. [2]
Overview
There is no Group B streptococcus (GBS) vaccine currently available to help mothers protect their newborns from GBS disease. Researchers are working on developing a vaccine, which may become available one day in the future. Phase I and II clinical trials among healthy, non-pregnant adults of monovalent polysaccharide-protein conjugate vaccines of GBS disease-associated types have shown these vaccines to be well tolerated and immunogenic. A recent, double-blind randomized trial of a conjugate vaccine against GBS serotype III among non-pregnant women of reproductive age found a significant delay in acquisition of colonization with the vaccine-serotype among vaccine recipients.[1]